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The Journal of Critical Care Medicine

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Oxidative Stress in the Critically Ill Polytrauma Patient

Dorel Săndesc
  • Corresponding author
  • Anesthesia and Intensive Care Clinic, Emergency County Hospital ”Pius Brînzeu”, Timişoara, Romania; Faculty of Medicine, ”Victor Babeş” University of Medicine and Pharmacy, Timişoara, Romania
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Published Online: 2015-08-06 | DOI: https://doi.org/10.1515/jccm-2015-0013


  • 1. Hybertson BM, Gao B, Bose SK, McCord JM. Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation. Mol Aspects Med. 2011;32:234–46.CrossrefWeb of ScienceGoogle Scholar

  • 2. Mendes Arent A, Souza LF De, Walz R, Dafre AL. Perspectives on molecular biomarkers of oxidative stress and antioxidant strategies in traumatic brain injury. Biomed Res Int. 2014; 2014:723060.Web of SciencePubMedGoogle Scholar

  • 3. Hohl A, Gullo JDS, Silva CCP, et al. Plasma levels of oxidative stress biomarkers and hospital mortality in severe head injury: A multivariate analysis. J Crit Care. 2012;27:523.e.11-9.Web of ScienceCrossrefPubMedGoogle Scholar

  • 4. Nathens AB, Neff MJ, Jurkovich GJ, et al. Randomized, prospective trial of antioxidant supplementation in critically ill surgical patients. Ann Surg. 2002;236:814–22.PubMedCrossrefGoogle Scholar

  • 5. Marik PE. The optimal endpoint of resuscitation in trauma patients. Crit Care. 2003;7:19–20.PubMedCrossrefGoogle Scholar

  • 6. Flörchinger B, Philipp A, Klose A, et al. Pumpless Extracorporeal Lung Assist: A 10-Year Institutional Experience. Ann Thorac Surg. 2008;86:410–7.CrossrefWeb of ScienceGoogle Scholar

  • 7. Bar-Or D, Bar-Or R, Rael LT, Brody EN. Oxidative stress in severe acute illness. Redox Biol. 2015;4:340–5.CrossrefWeb of ScienceGoogle Scholar

  • 8. Erecinska M, Thoresen M, Silver I. Effects of hypothermia on energy metabolism in Mammalian central nervous system. J Cereb Blood Flow Metab. 2003;23:513–30.PubMedGoogle Scholar

  • 9. Bosmann M, Ward PA. The inflammatory response in sepsis. Trends Immunol. 2013;34:129–36.PubMedCrossrefGoogle Scholar

  • 10. Brodska H, Valenta J, Malickova K, Kohout P, Kazda A, Drabek T. Biomarkers in critically ill patients with systemic inflammatory response syndrome or sepsis supplemented with high-dose selenium. J Trace Elem Med Biol. 2015;31:25–32.Web of ScienceCrossrefGoogle Scholar

  • 11. Crimi E, Sica V, Williams-Ignarro S, et al. The role of oxidative stress in adult critical care. Free Radic Biol Med. 2006; 40:398–406.Google Scholar

  • 12. Collier BR, Giladi A, Dossett LA, Dyer L, Fleming SB, Cotton BA. Impact of High-Dose Antioxidants on Outcomes in Acutely Injured Patients. J Parenter Enter Nutr. 2008;32:384–8.CrossrefWeb of ScienceGoogle Scholar

  • 13. Oudemans-van Straaten HM, Man A, de Waard MC. Vitamin C revisited. Crit Care. 2014;18:460.CrossrefGoogle Scholar

  • 14. Luca L, Rogobete AF, Bedreag OH. Oxidative stress and antioxidant therapy in critically ill polytrauma patients with severe head injury. J Crit Care Med. 2015;1:83-91.CrossrefGoogle Scholar

  • 15. Bedreag OH, Rogobete AF, Sărăndan M, et al. Oxidative stress and antioxidant therapy in traumatic spinal cord injuries. J Rom Anest Terap Int. 2014;21:123–9.Google Scholar

  • 16. Bedreag OH, Rogobete AF, Sarandan M, et al. Oxidative stress in severe pulmonary trauma in critical ill patients. Antioxidant therapy in patients with multiple trauma — a review. Anestezjol Intens Ter. 2015. doi: 10.5603/AIT.a2015.0030. [Epub ahead of print]CrossrefGoogle Scholar

About the article

Published Online: 2015-08-06

Published in Print: 2015-05-01

Citation Information: The Journal of Critical Care Medicine, ISSN (Online) 2393-1817, DOI: https://doi.org/10.1515/jccm-2015-0013.

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© Dorel Săndesc. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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