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Journal Of Cardiovascular Emergencies

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2457-5518
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Detection of Myocardial Injury Using miRNAs Expression as Genetic Biomarkers in Acute Cardiac Care

Alexandru Florin Rogobete
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
  • Clinic of Anesthesia and Intensive Care, “Pius Brînzeu” County Emergency Hospital, Timișoara, Romania
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/ Ovidiu Horea Bedreag
  • Corresponding author
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
  • Clinic of Anesthesia and Intensive Care, “Pius Brînzeu” County Emergency Hospital, Timișoara, Romania
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/ Sonia Elena Popovici
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
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/ Adriana Mariana Sas
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
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/ Adrian Tudor Stan
  • Faculty of Dental Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
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/ Emil Robert Stoicescu
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
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/ Dorel Sandesc
  • Faculty of Medicine, “Victor Babeș” University of Medicine and Pharmacy, Timișoara, Romania
  • Clinic of Anesthesia and Intensive Care, “Pius Brînzeu” County Emergency Hospital, Timișoara, Romania
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Published Online: 2016-12-30 | DOI: https://doi.org/10.1515/jce-2016-0025

Abstract

Cardiovascular disease is a leading cause of death globally. At present, there are many ways to diagnose this pathophysiology. The greatest disadvantages related to current biomarkers are their low specificity, low selectivity and low accuracy. A new method, extensively studied recently, is the expression of miRNAs, used as genetic biomarkers for the early diagnosis of cardiovascular diseases. This paper presents an update of miRNAs species expression that can serve as early diagnostic biomarkers and for the continuous monitoring of patients with cardiovascular disease.

Keywords: microRNA; acute myocardial infarction; acute cardiac care

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About the article

Received: 2016-09-10

Accepted: 2016-10-15

Published Online: 2016-12-30

Published in Print: 2016-12-01


Citation Information: Journal Of Cardiovascular Emergencies, ISSN (Online) 2457-5518, DOI: https://doi.org/10.1515/jce-2016-0025.

Export Citation

© 2016 Alexandru Florin Rogobete et al., published by De Gruyter Open. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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