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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, Zacharias

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Anti-Inflammatory, Antipyretic and Antioxidant Effect of Some Medicinal Plant Extracts

Attia H. Atta
  • Cairo University
/ Sanaa Kenawy
  • Cairo University
/ Amani Awaad
  • King Saud University
/ Reham El-Melegy
  • King Saud University
Published Online: 2011-05-02 | DOI: https://doi.org/10.2202/1553-3840.1086

The anti-inflammatory, antipyretic and antioxidant effect of the methanol extract of Alhgi maurorum, Conyza dioscoridis and Convolvulus fatmensis was investigated. The anti-inflammatory effect was studied using carageenan-induced rat paw edema, while the antipyretic effect was estimated using Brewer's yeast-induced hyperpyrexia in rats. The antioxidant activity was evaluated using 2,2-diphenyl-1-picryhydrazyl (DPPH) free radical scavenging activity method of different concentrations of the plant extracts using ascorbic acid as a standard antioxidant. The results revealed that oral administration of Alhgi maurorum and Convolvulus fatmensis at 1 g/ kg exhibited anti-inflammatory effect comparable to the standard diclofenac sodium (0.03 g/kg). The anti-inflammatory effect of Conyza dioscoridis appeared at lower doses 0.5g/kg. In all cases the maximum effect was obtained 2h after administration. None of the tested plant extracts showed antipyretic effect. The tested plant extracts showed variable degrees of antioxidant activity. Conyza dioscoridis showed the highest antioxidant effect (91.14%) and Alhgi maurorum has the least (28.78%) compared to the standard ascorbic acid (87.8%).

Keywords: A. maurorum; Conyza dioscoridis; C. fatmensis; medicinal plants; anti-inflammatory; antipyretic; antioxidants

About the article

Published Online: 2011-05-02

Citation Information: Journal of Complementary and Integrative Medicine, ISSN (Online) 1553-3840, DOI: https://doi.org/10.2202/1553-3840.1086. Export Citation

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