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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias

CiteScore 2017: 1.41

SCImago Journal Rank (SJR) 2017: 0.472
Source Normalized Impact per Paper (SNIP) 2017: 0.564

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Glucosinolates: The Phytochemicals of Nutraceutical Importance

Dhan Prakash / Charu Gupta
Published Online: 2012-07-02 | DOI: https://doi.org/10.1515/1553-3840.1611


Glucosinolates (thioglucoside-N-hydroxysulphates) constitute a homogeneous class of naturally occurring thiosaccharidic compounds mainly found in the botanical order Brassicales. They can be hydrolyzed by myrosinase to produce D-glucose and various other degradation products like isothiocyanates (ITCs)-depending on the aglycon part. The exact function of glucosinolates (GLSs) in the plant is unclear, however their potent odour and taste suggests a role in herbivore and microbial defense. They are known for their fungicidal, bacteriocidal, nematocidal and allelopathic properties and have recently attracted intense research interest because of their cancer chemo-protective attributes. Iso-thiocyanates, one of the hydrolyzed products, show best anti-carcinogenic activity.

Keywords: phytochemicals; nutraceuticals; glucosinolates; isothiocyanates; ascorbigen; methyl-ascorbigen

About the article

Published Online: 2012-07-02

Citation Information: Journal of Complementary and Integrative Medicine, Volume 9, Issue 1, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/1553-3840.1611.

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