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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias


CiteScore 2017: 1.41

SCImago Journal Rank (SJR) 2017: 0.472
Source Normalized Impact per Paper (SNIP) 2017: 0.564

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1553-3840
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The effect of electro-acupuncture on pro-oxidant antioxidant balance values in overweight and obese subjects: a randomized controlled trial study

M. Mazidi
  • Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
  • Institute of Genetics and Developmental Biology, International College, University of Chinese Academy of Science, Beijing 100101, China
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/ P. Abbasi-Parizad
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ H. Abdi
  • Key State Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
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/ B. Zhao
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ A. A. Rahsepar
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ S. Tavallaie
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ S. M. Parizadeh
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ P. Rezaie
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ M. Safariyan
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ M. Nematy
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ M. Mohammadi
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ M. Darbandi
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ S. Darbandi
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
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/ M. Ghayour-Mobarhan
  • Corresponding author
  • Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran
  • Department of Nutrition, School of Medicine. Biochemistry and Nutrition, Mashhad University of Medical Sciences (MUMS), Post code: 91779-48564Po BOX: 91775-379 Mashhad, Iran
  • Email
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/ G. A. Ferns
  • Division of Medical Education, Brighton and Sussex Medical School, University of Brighton, Rm 342, Mayfield House, Brighton BN1 9PH, UK
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Published Online: 2017-12-01 | DOI: https://doi.org/10.1515/jcim-2015-0081

Abstract

Objective

To undertake a randomized controlled trial in 196 obese subjects to examine the effect of electro-acupuncture on serum pro-oxidant antioxidant balance (PAB) values.

Methods

Subjects received authentic acupuncture (cases) or sham acupuncture (controls) for 6 weeks in combination with a low-calorie diet. In the following 6 weeks, they received the low-calorie diet alone. Serum PAB was measured at baseline, and 6 and 12 weeks later.

Results

We found that serum PAB values decreased significantly in the group receiving the authentic acupuncture compared to the sham treatment (p<0.001) at week 6, and whilst serum PAB increased significantly (p<0.05) in the second phase of the study, a significant difference between two groups remained at 12 weeks (p<0.05).

Conclusions

Electro-acupuncture in combination with a low-calorie diet was more effective at reducing serum PAB values in obese subjects compared to diet alone. Further work is required to determine the mechanism by which electro-acupuncture has this effect.

Keywords: electro-acupuncture; obesity; pro-oxidant antioxidant balance

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About the article

Mazidi M, Abbasi-Parizad P and Abdi H contributed equally.


Received: 2016-06-16

Accepted: 2017-09-27

Published Online: 2017-12-01


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Journal of Complementary and Integrative Medicine, Volume 15, Issue 2, 20150081, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/jcim-2015-0081.

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