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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias

4 Issues per year


CiteScore 2016: 1.04

SCImago Journal Rank (SJR) 2015: 0.401
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1553-3840
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Yogic practices on oxidative stress and of antioxidant level: a systematic review of randomized controlled trials

Rameswar PalORCID iD: http://orcid.org/0000-0001-6452-0951 / Navin Gupta
Published Online: 2017-10-25 | DOI: https://doi.org/10.1515/jcim-2017-0079

Abstract

Background

Many clinical trials have evaluated the oxidative stress reduction and enhancement of antioxidant status following yogic practices, but a review has not been reported earlier. Present study is designed to systematically review the effect of yogic practices on oxidative stress and antioxidant status.

Content

Using the MEDLINE, EMBASE SCOPEMED, and Indian database electronic searches were performed through August 2016 using the keywords yoga AND oxidative stress OR antioxidant which yielded 97 studies. Selections were made to include only experimental studies written in English, published in peer-reviewed journals and investigating the effects of regular yogic practices on oxidative stress and antioxidant status in these studies.

Summary and outlook

Search yielded a total of 97 trials, 11 met rigorous criteria for final systematic review. Healthy population showed overall enhancement of antioxidant status and reduced oxidative stress following yogic practices. Diabetic patients showed increased glutathione, vitamin C content and superoxide dismutase activity and decreased malondialdehyde content following yogic practices. Prediabetic and hypertensive patients showed reduced malondialdehyde content following yogic practices. Renal disease patients showed decreased protein oxidation, and increased superoxide dismutase activity following yogic practices. Regular yogic practices can improve antioxidants and reduce oxidative stress in healthy, diabetic, prediabetic, hypertensive and renal disease patients. Studies on other disease population have rarely been reported and studies are very few to conclude strongly.

Keywords: antioxidants; oxidative stress; redox status; yoga

References

  • [1]

    Harman D. Aging a theory based on free radical and radiation chemistry. J Gerontol. 1956;11:298–300.CrossrefPubMedGoogle Scholar

  • [2]

    Sen CK. Oxidants and antioxidants in exercise. J Appl Physiol. 1995;79:675–86.PubMedGoogle Scholar

  • [3]

    Pal R, Singh SN, Chatterjee A. Saha M. Age – related changes on cardiovascular system, autonomic function and levels of BDNF of healthy active males: role of yogic practice. Age (Omaha). 2014;36:9683. 1–17.Google Scholar

  • [4]

    Field T. Yoga clinical review. Complement Ther Clin Prac. 2010. DOI: CrossrefGoogle Scholar

  • [5]

    Madanmohan KU, Bhavanani AB, Vijayalakshmi P, Surendiran A. Effects of slow and fast pranayams on reaction time and cardiorespiratory variables. Ind J Physiol Pharmacol. 2005;49:313–18.Google Scholar

  • [6]

    Halder K, Chatterjee A, Kain TC, Pal R, Tomer OS, Saha M. Improvement in ventilatory function through yogic practices. Al Ameen J Med Sci. 2012;5:197–202.Google Scholar

  • [7]

    Hegde SV, Adhikari P, Kotian S, Pinto VJ, D’Souza S, D’Souza V. Effect of 3-month yoga on oxidative stress in type 2 diabetes with or without complications: a controlled clinical trial. Diabetes Care. 2011;34:2208–10.PubMedCrossrefGoogle Scholar

  • [8]

    Mahapure HH, Shete SU, Bera TK. Effect of yogic exercise on super oxide dismutase levels in diabetics. Int J Yoga. 2008;1:21–6.CrossrefPubMedGoogle Scholar

  • [9]

    Hegde SV, Adhikari P, Shetty S, Manjrekar P, D’Souza V. Effect of community-based yoga intervention on oxidative stress and glycemic parameters in prediabetes: a randomized controlled trial. Complement Ther Med. 2013;21:571–6.CrossrefPubMedWeb of ScienceGoogle Scholar

  • [10]

    Dhameja K, Singh S, Mustafa MD, Singh KP, Banerjee BD, Agarwal M, et al.. Therapeutic effect of yoga in patients with hypertension with reference to GST gene polymorphism. J Altern Complement Med. 2013;19:243–9.Web of SciencePubMedCrossrefGoogle Scholar

  • [11]

    Agte VV, Jahagirdar MU, Tarwadi KV. The effects of Sudarshan Kriya Yoga on some physiological and biochemical parameters in mild hypertensive patients. Ind J Physiol Pharmacol. 2011;55:183–7.Google Scholar

  • [12]

    Gordon L, McGrowder DA, Pena YT, Cabrera E. Lawrence-Wright MB. Effect of yoga exercise therapy on oxidative stress indicators with end-stage renal disease on hemodialysis. Int J Yoga. 2013;6:31–8.CrossrefPubMedGoogle Scholar

  • [13]

    Pal R, Singh SN, Halder K, Tomer OS, Mishra AB, Saha M. Effects of yogic practice on metabolism and antioxidant - redox status of physically active males. J Phys Act Health. 2015;12:579–87.Web of ScienceCrossrefPubMedGoogle Scholar

  • [14]

    Pal R, Singh SN, Halder K, Tomer OS, Mishra AB, Saha M. Effect of yogic practices on age related changes in oxygen metabolism and antioxidant – redox status. J Exp and Int Med. 2013;3:305–12.CrossrefGoogle Scholar

  • [15]

    Higgins JP, Altman DG, Gøtzsche PC, Jüni P, Moher D, Oxman AD, et al. The Cochrane collaboration’s tool for assessing risk of bias in randomised trials. Bmj. 2011;343:d5928.CrossrefWeb of ScienceGoogle Scholar

  • [16]

    Sinha S, Singh SN, Monga YP, Ray US. Improvement of glutathione and total antioxidant status with yoga. Altern Complement Med 2007;13:1085-90. doi:2007.0567.CrossrefWeb of ScienceGoogle Scholar

  • [17]

    Bhattacharya S, Pandey US, Verma NS. Improvement in oxidative status with yogic breathing in young healthy males. Ind J Physiol Pharmacol. 2002;46:349–54.Google Scholar

  • [18]

    Lim SA, Cheong KJ. Regular yoga practice improves antioxidant status, immune function, and stress hormone releases in young healthy people: a randomized, double-blind, controlled pilot study. J Altern Complement Med. 2015;21:530–8.Web of SciencePubMedCrossrefGoogle Scholar

  • [19]

    Patil SG, Dhanakshirur GB, Aithala MR, Naregal G, Das KK. Effect of yoga on oxidative stress in elderly with grade-I hypertension: a randomized controlled study. J Clin Diagn Res. 2014;8(7). DOI: CrossrefPubMedGoogle Scholar

  • [20]

    Habig WH, Pabst MJ, Jakoby WB. Glutathione S – Transferases the first enzymatic step in mercapturic acid formation. J Biol Chem. 1974;249:7130–39.PubMedGoogle Scholar

About the article

Received: 2017-06-01

Accepted: 2017-09-08

Published Online: 2017-10-25


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.


Citation Information: Journal of Complementary and Integrative Medicine, 20170079, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/jcim-2017-0079.

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