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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias

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Medicinal plants’ use among patients with dyslipidemia: an Iranian cross-sectional survey

Mohammad Hashem Hashempur
  • Department of Persian Medicine, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran (Islamic Republic of)
  • Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Seyed Hamdollah Mosavat
  • Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (Islamic Republic of)
  • Research Center for Psychiatry and Behavior Science, Shiraz University of Medical Sciences, Shiraz, Iran (Islamic Republic of)
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Mojtaba Heydari
  • Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (Islamic Republic of)
  • Department of Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran (Islamic Republic of)
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Mesbah Shams
  • Corresponding author
  • Endocrine and Metabolism Research Center, Shiraz University of Medical Sciences, Shiraz, Iran (Islamic Republic of)
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2018-11-03 | DOI: https://doi.org/10.1515/jcim-2018-0101



Despite growing demand for medicinal plants, there is little data about their use by patients with dyslipidemia. We aimed to determine the prevalence, pattern, and associated factors for the use of medicinal plants among patients with dyslipidemia.


A 17-item semi-structured questionnaire was filled out by 195 patients with dyslipidemia in a cross-sectional study carried out in two academic endocrinology clinics in Shiraz, Iran. The questionnaire comprised of three main domains of demographic data (6 questions), clinical data (2 of them), and data related to the use of medicinal plants (totally 9 questions).


A total of 77.4% of patients took medicinal plants. The most common medicinal herbs used by dyslipidemic patients were Zataria multiflora, Cinnamomum zeylanicum, and Zingiber officinale. Duration of dyslipidemia was significantly longer in herbal users than non-herbal users (p=0.04). Patients believing that concomitant use of conventional drugs and herbal preparations had synergic positive effects in addition to those persuaded that herbal preparations possessed less side effects, were significantly more likely to use medicinal plants (p=0.008 and 0.005, respectively). Additionally, most of the medicinal herb users (87.4%) changed neither the pattern nor the dosage of their medications all during herbal preparations use.


This study demonstrated a high prevalence of medicinal plants’ use among patients with dyslipidemia, which was associated with the duration of dyslipidemia, patients’ viewpoints about herbal preparations’ synergic positive effects, and their fewer side effects.

Keywords: complementary therapies; dyslipidemia; medicinal plants; phytotherapy; prevalence; traditional Persian medicine


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About the article

Received: 2018-06-20

Accepted: 2018-10-04

Published Online: 2018-11-03

Author contributions: MHH, MS, MH and MS participated in the design of the study. MHH, SHM and MH conducted the interviews and identified all medicinal plants reported. MH contributed to the statistical analysis. SHM and MHH wrote the first draft of the manuscript. All authors contributed to interpretation of the results and the final manuscript. All authors read and approved the final manuscript.

Research funding: Fasa University of Medical Sciences (Funder Id: 10.13039/501100006402), (96133)

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

Citation Information: Journal of Complementary and Integrative Medicine, 20180101, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/jcim-2018-0101.

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