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Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias

CiteScore 2017: 1.41

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Pharmacological and nutritive potential of Euphorbia granulata

Saeed Ahmad
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Samya Perveen
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Muhammad Adeel Arshad
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Tayyeba Rehman
  • Corresponding author
  • University College of Conventional Medicine, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
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Published Online: 2018-10-12 | DOI: https://doi.org/10.1515/jcim-2018-0149



Euphorbia granulata is herb of family Euphorbiaceae having several traditional uses. The aim of the study is to summarize reported nutritional and medicinal value along with ethnomedical records.


The papers on nutritional and medicinal value of E. granulata are collected from electronic search engines (Google Scholar, PubMed). Synonyms are confirmed from “The plant List.”


Pharmacological studies suggest that the extracts of E. granulata possess antioxidant, antibacterial, antifungal, diuretic, antiulcerative colitis and spasmolytic properties. Moreover, it is rich with nutritive components such as carbohydrates, lipid contents (saturated and unsaturated fatty acids), minerals and protein (amino acids). Toxicological data of E. granulata showed that it may be poisonous and toxic at higher doses.


Research studies suggest that E. granulata has sufficient pharmacological potential against several diseases including infections, gastric ulcers, anuria, oliguria and spasmodic disorders; however, more research is required to confirm its pharmacological potential. Moreover, dose fixation studies should be carried out to avoid its toxicity.

Keywords: diuretic; Euphorbia granulate; nutritive value; ulcerative colitis


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About the article

Received: 2018-08-19

Accepted: 2018-08-31

Published Online: 2018-10-12

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report or in the decision to submit the report for publication.

Citation Information: Journal of Complementary and Integrative Medicine, 20180149, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/jcim-2018-0149.

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