Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Journal of Complementary and Integrative Medicine

Editor-in-Chief: Lui, Edmund

Ed. by Ko, Robert / Leung, Kelvin Sze-Yin / Saunders, Paul / Suntres, PH. D., Zacharias


CiteScore 2017: 1.41

SCImago Journal Rank (SJR) 2017: 0.472
Source Normalized Impact per Paper (SNIP) 2017: 0.564

Online
ISSN
1553-3840
See all formats and pricing
More options …

Pharmacological and nutritive potential of Euphorbia granulata

Saeed Ahmad
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Samya Perveen
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Muhammad Adeel Arshad
  • Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Tayyeba Rehman
  • Corresponding author
  • University College of Conventional Medicine, Faculty of Pharmacy and Alternative Medicine, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2018-10-12 | DOI: https://doi.org/10.1515/jcim-2018-0149

Abstract

Background

Euphorbia granulata is herb of family Euphorbiaceae having several traditional uses. The aim of the study is to summarize reported nutritional and medicinal value along with ethnomedical records.

Methods

The papers on nutritional and medicinal value of E. granulata are collected from electronic search engines (Google Scholar, PubMed). Synonyms are confirmed from “The plant List.”

Results

Pharmacological studies suggest that the extracts of E. granulata possess antioxidant, antibacterial, antifungal, diuretic, antiulcerative colitis and spasmolytic properties. Moreover, it is rich with nutritive components such as carbohydrates, lipid contents (saturated and unsaturated fatty acids), minerals and protein (amino acids). Toxicological data of E. granulata showed that it may be poisonous and toxic at higher doses.

Conclusion

Research studies suggest that E. granulata has sufficient pharmacological potential against several diseases including infections, gastric ulcers, anuria, oliguria and spasmodic disorders; however, more research is required to confirm its pharmacological potential. Moreover, dose fixation studies should be carried out to avoid its toxicity.

Keywords: diuretic; Euphorbia granulate; nutritive value; ulcerative colitis

References

  • [1]

    Malik S, Ahmad S, Sadiq A, Alam K, Wariss HM, Ahmad I, et al. A comparative ethno-botanical study of Cholistan (an arid area) and Pothwar (a semi-arid area) of Pakistan for traditional medicines. J Ethnobiol Ethnomed. 2015;11:31.CrossrefPubMedWeb of ScienceGoogle Scholar

  • [2]

    Bousselessela H, Yahia M, Mahboubi A, Benbia S, Massinissa Y. Antioxidant and antibacterial activity of alkaloids and terpenes extracts from Euphorbia granulata. J Med Eng Techno. 2013;7:166–69.Google Scholar

  • [3]

    Hameed M, Ashraf M, Al-Quriany F, Nawaz T, Ahmad MSA, Younis A, et al. Medicinal flora of the Cholistan desert: a review. Pak J Bot. 2011;43:39–50.Google Scholar

  • [4]

    Ahmad S, Alam K, Wariss H, Anjum S, Mukhtar M. Ethnobotanical studies of plant resources of Cholistan desert, Pakistan. Int J Sci Res. 2014;3:1782–88.Google Scholar

  • [5]

    Saleem H, Ahmad I, Gill MSA. Phytochemical screening and diuretic activity of Euphorbia granulata. Bangladesh J Pharmacol. 2015;10:584–87.Web of ScienceCrossrefGoogle Scholar

  • [6]

    Ahmad I, Khan A-U, Chaudhary BA, Janbaz KH, Uzair M, Akhtar M, et al. Antifungal and antispasmodic activities of the extracts of Euphorbia granulata. J Med Plants Res. 2012;6:19–23.Google Scholar

  • [7]

    Rizk AFM. The chemical constituents and economic plants of the Euphorbiaceae. Bot J Linean Soc. 1987;94:293–326.CrossrefGoogle Scholar

  • [8]

    AL-Naimi RA. Toxicopathological study on the effect of different toxic doses of Euphorbia granulata F. crude extract in albino mice. Iraqi J of Vet Med. 2011;35:119–28.Google Scholar

  • [9]

    Anwer S, Ali Q, Ali M, Khalid H, Ahmad A, Ali A, et al. Assessment of association among various morphological traits of Euphorbia granulata, Euphorbia hirta, Fumaria indica and Parthenium hysterophorus. Nat Sci. 2015;13:47–51.Google Scholar

  • [10]

    Kinghorn AD, Evans F. A biological screen of selected species of the genus Euphorbia for skin irritant effects. Planta Med. 1975;28:325–35.CrossrefGoogle Scholar

  • [11]

    Awaad AS, El‐Meligy RM, Al‐Jaber NA, Al‐Muteeri HS, Zain ME, Alqasoumi SI, et al. Anti‐ulcerative colitis activity of compounds from Euphorbia granuleta Forssk. Phytother Res. 2013;27:1729–34.PubMedCrossrefGoogle Scholar

  • [12]

    Cáceres A, Girón LM, Martínez AM. Diuretic activity of plants used for the treatment of urinary ailments in Guatemala. J Ethnopharmacol. 1987;19:233–45.CrossrefPubMedGoogle Scholar

  • [13]

    Ahmad S, Hassan A, Abbasi WM, Rehman T. Phytochemistry and pharmacological potential of Cassia absus – a review. J Pharm Pharmacol. 2018;70:27–41.CrossrefPubMedWeb of ScienceGoogle Scholar

  • [14]

    Abbasi WM, Ahmad S, Perveen S, Rehman T. Preliminary phytochemical analysis and in vivo evaluation of antipyretic effects of hydromethanolic extract of Cleome scaposa leaves. eJTCM. 2018;8:147–49.Google Scholar

  • [15]

    Ahmad S, Rehman T, Abbasi WM, Zaman MM. Analysis of antioxidant activity and total phenolic content of some homeopathic mother tinctures. Indian J Res Homeopathy. 2017;11:21–5.CrossrefGoogle Scholar

  • [16]

    Zaman MM, Shaad MA, Ahmad S, Abbasi WM, Rehman T. Comparative analysis of antibacterial activity of povidone iodine and homoeopathic mother tinctures as antiseptics. Indian J Res Homoeopathy. 2016;10:36–41.CrossrefGoogle Scholar

  • [17]

    Awaad AS, Alothman MR, Zain YM, Zain GM, Alqasoumi SI, Hassan DA. Comparative nutritional value and antimicrobial activities between three Euphorbia species growing in Saudi Arabia. Saudi Pharm J. 2017;25:1226–30.Web of ScienceCrossrefPubMedGoogle Scholar

  • [18]

    Parvez M, Hussain F, Ahmad B, Ali J. Euphorbia granulata Forssk as a source of mineral supplement. Am Eurasian J Agric Environ Sci. 2013;13:1108–13.Google Scholar

About the article

Received: 2018-08-19

Accepted: 2018-08-31

Published Online: 2018-10-12


Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis and interpretation of data; in the writing of the report or in the decision to submit the report for publication.


Citation Information: Journal of Complementary and Integrative Medicine, 20180149, ISSN (Online) 1553-3840, DOI: https://doi.org/10.1515/jcim-2018-0149.

Export Citation

© 2018 Walter de Gruyter GmbH, Berlin/Boston.Get Permission

Comments (0)

Please log in or register to comment.
Log in