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Journal of Integrative Bioinformatics

Editor-in-Chief: Schreiber, Falk / Hofestädt, Ralf

Managing Editor: Sommer, Björn

Ed. by Baumbach, Jan / Chen, Ming / Orlov, Yuriy / Allmer, Jens

Editorial Board: Giorgetti, Alejandro / Harrison, Andrew / Kochetov, Aleksey / Krüger, Jens / Ma, Qi / Matsuno, Hiroshi / Mitra, Chanchal K. / Pauling, Josch K. / Rawlings, Chris / Fdez-Riverola, Florentino / Romano, Paolo / Röttger, Richard / Shoshi, Alban / Soares, Siomar de Castro / Taubert, Jan / Tauch, Andreas / Yousef, Malik / Weise, Stephan / Hassani-Pak, Keywan

CiteScore 2017: 0.77

SCImago Journal Rank (SJR) 2017: 0.336

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Volume 1, Issue 1


Simulated Cell Division Processes of the Xenopus Cell Cycle Pathway by Genomic Object Net

Mika Matsui
  • Faculty of Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi 753-8512, Japan Japan
  • Oshima National College of Maritime Technology, 1091-1, Oshima-cho, Yamaguchi-ken 742-2193, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Sachie Fujita / Shunichi Suzuki / Hiroshi Matsuno / Satoru Miyano
  • Human Genome Center, Insititute of Medical Science, University of Tokyo,4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-09-30 | DOI: https://doi.org/10.1515/jib-2004-3


Matsuno et al.[1] modeled and simulated that multicellular patterning by the Drosophila Delta-Notch signaling pathway by using the software “Genomic Object Net” which was developed based on hybrid functional Petri net (HFPN) architecture. In this model, cellular formation is fixed throughout the simulation. This paper constructs an HFPN model of the Xenopus cell cycle pathway, which includes the mechanism for cell division control as well as checkpoint processes. This model simulates dynamic cell division processes of the early Xenopus embryo, including the changes in cell division cycles from synchronous to asynchronous.

About the article

Published Online: 2016-09-30

Published in Print: 2004-12-01

Citation Information: Journal of Integrative Bioinformatics, Volume 1, Issue 1, Pages 27–37, ISSN (Online) 1613-4516, DOI: https://doi.org/10.1515/jib-2004-3.

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© 2004 The Author(s). Published by Journal of Integrative Bioinformatics.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. BY-NC-ND 4.0

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