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Journal of Integrative Bioinformatics

Editor-in-Chief: Schreiber, Falk / Hofestädt, Ralf

Managing Editor: Sommer, Björn

Ed. by Baumbach, Jan / Chen, Ming / Orlov, Yuriy / Allmer, Jens

Editorial Board: Giorgetti, Alejandro / Harrison, Andrew / Kochetov, Aleksey / Krüger, Jens / Ma, Qi / Matsuno, Hiroshi / Mitra, Chanchal K. / Pauling, Josch K. / Rawlings, Chris / Fdez-Riverola, Florentino / Romano, Paolo / Röttger, Richard / Shoshi, Alban / Soares, Siomar de Castro / Taubert, Jan / Tauch, Andreas / Yousef, Malik / Weise, Stephan / Hassani-Pak, Keywan


CiteScore 2018: 0.90

SCImago Journal Rank (SJR) 2018: 0.315

Open Access
Online
ISSN
1613-4516
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Volume 9, Issue 2

Issues

Oncology In Vivo Data Integration for Hypothesis Generation

Jia Wei
  • Corresponding author
  • AstraZeneca Innovation Center China, R&D Information China, Building 7, No.898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China
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  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ming Chen
  • AstraZeneca Innovation Center China, R&D Information China, Building 7, No.898 Halei Road, Zhangjiang Hi-Tech Park, Shanghai 201203, China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2016-10-18 | DOI: https://doi.org/10.1515/jib-2012-193

Summary

AstraZeneca’s Oncology in vivo data integration platform brings multidimensional data from animal model efficacy, pharmacokinetic and pharmacodynamic data to animal model profiling data and public in vivo studies. Using this platform, scientists can cluster model efficacy and model profiling data together, quickly identify responder profiles and correlate molecular characteristics to pharmacological response. Through meta-analysis, scientists can compare pharmacology between single and combination treatments, between different drug scheduling and administration routes.

About the article

Published Online: 2016-10-18

Published in Print: 2012-06-01


Citation Information: Journal of Integrative Bioinformatics, Volume 9, Issue 2, Pages 19–27, ISSN (Online) 1613-4516, DOI: https://doi.org/10.1515/jib-2012-193.

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© 2012 The Author(s). Published by Journal of Integrative Bioinformatics.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. BY-NC-ND 4.0

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