Journal of Inverse and Ill-posed Problems
Editor-in-Chief: Kabanikhin, Sergey I.
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Inverse problems and model validation: an example from latent virus reactivation
1Center For Research in Scientific Computation, North Carolina State University, Raleigh, N.C. 27695-8205, USA. Email: (email)
2Center For Research in Scientific Computation, North Carolina State University, Raleigh, N.C. 27695-8205, USA. Email: (email)
3Center for Naval Analyses, Alexandria, VA 22311, USA. Email: (email)
4Department of Dental Ecology, School of Dentistry, University of North Carolina, Chapel Hill, N.C. 27599, USA. Email: (email)
Citation Information: Journal of Inverse and Ill-posed Problems jiip. Volume 15, Issue 3, Pages 225–241, ISSN (Online) 1569-3953, ISSN (Print) 0928-0219, DOI: 10.1515/jiip.2007.012, June 2007
- Published Online:
We consider a least squares inverse problem with a model for inducer-mediated reactivation of latent viruses. We illustrate the difficulties associated with the lack of sufficient data (quantity as well as form) in such problems. The modeling and estimation efforts described suggest new experiments as well as needed model extensions.
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