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Journal of Interdisciplinary Medicine

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Intracoronary Shear Stress and CT Characteristics of Vulnerable Coronary Plaques

Annabella Benedek
Published Online: 2017-11-08 | DOI: https://doi.org/10.1515/jim-2017-0077


Vulnerable coronary plaques are associated with a significant risk for rupture, and the ability to detect their characteristic features is of extreme importance, as timely detection of rupture-prone plaques could lead to the appropriate initiation of adequate therapeutic measures and prevent the evolution to an acute coronary event. The most common features of vulnerability in coronary plaques are represented by the presence of low density atheroma, a thin fibrous cap, spotty calcifications, and positive remodeling. However, there is still a huge amount of information to be learned about the role of local forces, represented by the shear stress, on the plaque vulnerability. This clinical update aims to present the most recent advances in the field of knowledge regarding the relation between shear stress and plaque vulnerability, starting from the hypothesis that shear stress significantly correlates with the CT features of plaque vulnerability and can represent a new marker of vulnerability in coronary artery plaques.

Keywords: shear stress; computed tomography angiography; plaque vulnerability


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About the article

Received: 2017-07-10

Accepted: 2017-08-15

Published Online: 2017-11-08

Published in Print: 2017-09-01

Citation Information: Journal of Interdisciplinary Medicine, Volume 2, Issue 3, Pages 242–244, ISSN (Online) 2501-8132, DOI: https://doi.org/10.1515/jim-2017-0077.

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© 2017 Annabella Benedek, published by De Gruyter Open. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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