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Roth, Christian

Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

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Volume 23, Issue 10 (Jan 2010)


Effects of a Structured Exercise Program on Insulin Resistance, Inflammatory Markers and Physical Fitness in Obese Korean Children

Hyun-Wook Chae
  • Department of Pediatrics, Yonsei University, Seoul, Korea
/ Yu-Na Kwon
  • Department of Physical Education, Yonsei University, Seoul, Korea
/ Young-Jun Rhie
  • Department of Pediatrics, Korea University College of Medicine, all of Seoul, Korea
/ Ho-Seong Kim
  • Department of Pediatrics, Yonsei University, Seoul, Korea
/ Yu-Sik Kim
  • Department of Physical Education, Yonsei University, Seoul, Korea
/ Il-Young Paik
  • Department of Physical Education, Yonsei University, Seoul, Korea
/ Sang-Hoon Suh
  • Corresponding author
  • Department of Physical Education, Yonsei University, Seoul, Korea
/ Duk-Hee Kim
  • Corresponding author
  • Department of Pediatrics, Yonsei University, Seoul, Korea


Thirty-eight obese Korean children (21 boys, 17 girls), whose ages were between 9 and 15, were divided into either the intervention group (19 obese children: BMI>95P) or the age- and sex-matched obese control group. The intervention group performed an intensive exercise program under the supervision of educated instructors for 12 weeks (90 minutes/day, two days/week) and received lifestyle modification counseling using food diaries and phone calls. The control group participated in conventional counseling at an out-patient clinic. The intervention group appeared to have more improvement of body weight, body composition, serum lipid profiles and high-sensitivity C-reactive protein (hs-CRP) levels (P < 0.05) but without changes in serum adiponectin level. HOMA-IR decreased from 2.3 to 1.3 in the intervention group. Maximal oxygen consumption (VO2 max) and other physical fitness parameters were significantly improved after the intervention program (P < 0.05).

KEY WORDS: exercise; childhood obesity; insulin resistance; adiponectin; physical fitness

About the article

Corresponding author: Sang-Hoon Suh,

Corresponding author: Duk-Hee Kim, MD,

Published in Print: 2010-10-01

Citation Information: Journal of Pediatric Endocrinology and Metabolism, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem.2010.168. Export Citation

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