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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Toppari, Jorma

IMPACT FACTOR 2017: 1.086

CiteScore 2017: 1.07

SCImago Journal Rank (SJR) 2017: 0.465
Source Normalized Impact per Paper (SNIP) 2017: 0.580

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Volume 23, Issue 10


Case Series of Neonatal Hypocalcemia due to Pseudohypoparathyroidism

Soumya Patra
  • Corresponding author
  • *Kalawati Saran Children's Hospital & Lady Hardinge Medical College, New Delhi-1, India
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Varinder Singh / Harish K. Pemde / Jagdish Chandra


Four children; all between 10-40 days of age, were admitted with multiple episodes of multifocal seizure. After admission blood investigation was carried out and they were found to have hypocalcemia, hyperphosphatemia; kidney function tests were normal. Serum parathyroid hormone was highly elevated and serum magnesium level was found to be normal in these patients. The infants did not have any other features of pseudohypoparathyroidism. The seizure was initially resistant to intravenous calcium therapy and later responded to oral calcitriol and calcium therapy. The diagnosis of pseudohypoparathyroidism was made according to biochemical investigations. The infants were symptom-free during follow-up and the biochemistry reports were also normalized. One of the infants was also suffering from neonatal hepatitis, due to CMV infection.

KEY WORDS: Pseudohypoparathyroidism; hypocalcemic seizures; infant

About the article

Corresponding Author: Dr. Soumya Patra,

Published in Print: 2010-10-01

Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 23, Issue 10, Pages 1073–1075, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem.2010.169.

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