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Roth, Christian

Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

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In This Section
Volume 24, Issue 1-2 (Mar 2011)

Issues

Pros of priming in the diagnosis of growth hormone deficiency

E. Nazli Gonc
  • Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey
  • Email:
/ Alev Ozon
  • Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey
/ Ayfer Alikasifoglu
  • Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey
/ Nurgun Kandemir
  • Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey
Published Online: 2011-03-16 | DOI: https://doi.org/10.1515/jpem.2011.076

Abstract

Priming with sex steroids in stimulation tests for the diagnosis of GHD is still under debate. Most of the data on utility of priming during GH stimulation so far seem to support its use in the diagnosis of GHD in childhood. There is a propensity to treat growth retarded children who test subnormally to stimulation tests with GH. However, some studies analyzing the final height or height gain during GH treatment in such children failed to show any improvement in height. This paper summarizes previous studies on priming to analyze the utility of priming as a valid method to better the diagnostic capacity of the test.

Keywords: final height; growth hormone; growth hormone deficiency; growth hormone stimulation tests; priming; sex steroids

About the article

Corresponding author: E. Nazli Gonc, Department of Pediatric Endocrinology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey Phone: +903123051124, Fax: +903123121809


Published Online: 2011-03-16

Published in Print: 2011-03-01



Citation Information: Journal of Pediatric Endocrinology and Metabolism, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem.2011.076. Export Citation

Citing Articles

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[1]
Evan Graber and Robert Rapaport
Pediatric Annals, 2012, Volume 41, Number 4, Page e65
[2]
Roberto Lanes
Journal of Pediatric Endocrinology and Metabolism, 2011, Volume 24, Number 1-2

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