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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Ogata, Tsutomu / Toppari, Jorma

12 Issues per year


IMPACT FACTOR 2017: 1.086

CiteScore 2017: 1.07

SCImago Journal Rank (SJR) 2017: 0.465
Source Normalized Impact per Paper (SNIP) 2017: 0.580

Online
ISSN
2191-0251
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Volume 25, Issue 1-2

Issues

Autoimmune thyroid disease and allergic contact dermatitis: two immune-related pathologies in the same patient

Marek Niedziela
  • Department of Pediatric Endocrinology and Rheumatology, Second Chair of Pediatrics, Poznan University of Medical Sciences, Poznan, Poland
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/ Sasha Bluvshteyn-Walker
  • Department of Pediatric Endocrinology and Rheumatology, Second Chair of Pediatrics, Poznan University of Medical Sciences, Poznan, Poland
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Published Online: 2012-02-17 | DOI: https://doi.org/10.1515/jpem-2011-0392

A 12-year-old girl presented signs and symptoms of hyperthyroidism. She had a firm goiter (II°) and she stated that she felt constant warmth, nervousness and experienced palpitations. Autoimmune hyperthyroidism was diagnosed (TSH 0.022 mIU/L↓; fT4 21.0 pmol/L; fT3 7.5 pmol/L↑; antithyroperoxidase antibodies 1148.0 U/mL↑; antithyroglobulin antibodies 41.4 U/mL; thyroid-stimulating hormone receptor antibodies 2.3 U/L↑). Thyroid ultrasound showed multiple hypoechogenic areas with increased vascular flow. During treatment with methimazole, a small hyperpigmented and moderately irritated region was found on the right side of the umbilicus. It was not an allergic skin reaction to methimazole but the classic contact allergic dermatitis, probably a result of nickel in her belt. Two years after stopping the treatment she returned to clinics. She was euthyroid but manifested a firm goiter and ultrasonographic features of autoimmune thyroid disease. The diagnostic work-up concerning antithyroid antibodies is mandatory to confirm the ongoing autoimmune process with a long-term significance.

Keywords: allergic contact dermatitis; autoimmune thyroid diseases; children

About the article

Corresponding author: Marek Niedziela, 27/33 Szpitalna Street, 60-572 Poznan, Poland Phone: +48 61 8491481, Fax: +48 61 8480291


Received: 2011-08-14

Accepted: 2011-11-21

Published Online: 2012-02-17

Published in Print: 2012-02-01


Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 25, Issue 1-2, Pages 31–32, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem-2011-0392.

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©2012 by Walter de Gruyter Berlin Boston.Get Permission

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