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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Toppari, Jorma


IMPACT FACTOR 2018: 1.239

CiteScore 2018: 1.22

SCImago Journal Rank (SJR) 2018: 0.507
Source Normalized Impact per Paper (SNIP) 2018: 0.562

Online
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2191-0251
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Volume 25, Issue 3-4

Issues

Hypophosphatemia in small for gestational age extremely low birth weight infants receiving parenteral nutrition in the first week after birth

Go Ichikawa / Yoshiyuki Watabe / Hiroshi Suzumura / Toshimi Sairenchi
  • Department of Public Health, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Takashi Muto
  • Department of Public Health, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Osamu Arisaka
Published Online: 2012-03-16 | DOI: https://doi.org/10.1515/jpem-2011-0485

Abstract

Objectives: To investigate the risk of hypophosphatemia and hypercalcemia in small for gestational age (SGA) extremely low birth weight infants (ELBWI) receiving parenteral nutrition.

Methods: A retrospective review of 58 ELBWI was conducted. Serum calcium (Ca) and phosphate (PO4) concentrations on days 1 and 8 after birth were examined for associations with body measurements and nutritional factors in the 1st week of life.

Results: Lower birth weight standard deviation (SD) scores were correlated with hypophosphatemia and hypercalcemia in SGA ELBWI on day 8. Higher parenteral amino acid (AA) administration was correlated with hypophosphatemia on day 8. SGA ELBWI exhibited lower serum PO4concentrations compared to appropriate for gestational age (AGA) ELBWI on day 8.

Conclusions: This is the 1st study to report that parenteral nutrition, in the first 7 days after birth for the treatment of SGA ELBWI, was correlated with hypophosphatemia and hypercalcemia. It is important to determine an ideal nutrition protocol for treatment of SGA ELBWI.

Keywords: hypercalcemia; hypophosphatemia; nutrition; small for gestational age

About the article

Corresponding author: Go Ichikawa, MD, Department of Pediatrics, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Shimotuga-gun, Tochigi 321–0293, Japan Phone: +81-282-861111, Fax: +81-282-867521


Received: 2011-12-19

Accepted: 2012-02-13

Published Online: 2012-03-16

Published in Print: 2012-04-01


Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 25, Issue 3-4, Pages 317–321, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem-2011-0485.

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