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Licensed Unlicensed Requires Authentication Published by De Gruyter December 18, 2013

Are the characteristics of thyroid cancer different in young patients?

  • Aybala Agac Ay EMAIL logo , Suat Kutun and Abdullah Çetin

Abstract

Background: Thyroid carcinoma in pediatric patients continues to be a rare albeit significant condition because local recurrence or distant metastases may be revealed during its diagnosis, or even years after completion of treatment.

Methods: This study was prepared by retrospective analysis of patient files to focus on the clinical presentation of thyroid carcinoma in pediatric patients, and proposes to investigate the clinical parameters that differ from, or that correspond to, those in adult patients.

Subjects: A total of 108 patients, of whom 22 were children and adolescents and 86 were adults, and who were operated on for differentiated thyroid carcinoma during the period 2001–2009, were included in the study.

Results: The rate of large thyroid, multinodular goiter, or tumor >1 cm was significantly higher in the adult group than in the pediatric group. Our analysis also revealed that that the frequency of lymph node metastasis was significantly higher in the pediatric group than in the adult group. Moreover, the frequencies of total lymph node and positive lymph node presentations were significantly higher in the pediatric group than in the adult group.

Conclusion: Although thyroid carcinoma has a good prognosis in young patients, one must stress that late diagnosis and ineffective treatment are the main criteria for poor prognosis and, most important, that it is advisable to keep the management of thyroid carcinoma on a path that differs from the management of adult thyroid carcinomas, in nearly all aspects from presentation to treatment.


Corresponding author: Aybala Agac Ay, School of Medicine, General Surgery Department, Kırıkkale University, Kırıkkale 71500, Turkey, Phone: +90 5052301566, E-mail:

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Received: 2013-5-17
Accepted: 2013-10-30
Published Online: 2013-12-18
Published in Print: 2014-5-1

©2014 by Walter de Gruyter Berlin/Boston

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