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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Toppari, Jorma


IMPACT FACTOR 2018: 1.239

CiteScore 2018: 1.22

SCImago Journal Rank (SJR) 2018: 0.507
Source Normalized Impact per Paper (SNIP) 2018: 0.562

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2191-0251
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Volume 27, Issue 5-6

Issues

Are the characteristics of thyroid cancer different in young patients?

Aybala Agac Ay
  • Corresponding author
  • School of Medicine, General Surgery Department, Kırıkkale University, Kırıkkale 71500, Turkey
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Suat Kutun / Abdullah Çetin
Published Online: 2013-12-18 | DOI: https://doi.org/10.1515/jpem-2013-0192

Abstract

Background: Thyroid carcinoma in pediatric patients continues to be a rare albeit significant condition because local recurrence or distant metastases may be revealed during its diagnosis, or even years after completion of treatment.

Methods: This study was prepared by retrospective analysis of patient files to focus on the clinical presentation of thyroid carcinoma in pediatric patients, and proposes to investigate the clinical parameters that differ from, or that correspond to, those in adult patients.

Subjects: A total of 108 patients, of whom 22 were children and adolescents and 86 were adults, and who were operated on for differentiated thyroid carcinoma during the period 2001–2009, were included in the study.

Results: The rate of large thyroid, multinodular goiter, or tumor >1 cm was significantly higher in the adult group than in the pediatric group. Our analysis also revealed that that the frequency of lymph node metastasis was significantly higher in the pediatric group than in the adult group. Moreover, the frequencies of total lymph node and positive lymph node presentations were significantly higher in the pediatric group than in the adult group.

Conclusion: Although thyroid carcinoma has a good prognosis in young patients, one must stress that late diagnosis and ineffective treatment are the main criteria for poor prognosis and, most important, that it is advisable to keep the management of thyroid carcinoma on a path that differs from the management of adult thyroid carcinomas, in nearly all aspects from presentation to treatment.

Keywords: adolescent patients; pediatric patients; thyroid cancer

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About the article

Corresponding author: Aybala Agac Ay, School of Medicine, General Surgery Department, Kırıkkale University, Kırıkkale 71500, Turkey, Phone: +90 5052301566, E-mail:


Received: 2013-05-17

Accepted: 2013-10-30

Published Online: 2013-12-18

Published in Print: 2014-05-01


Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 27, Issue 5-6, Pages 497–502, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem-2013-0192.

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