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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Toppari, Jorma

IMPACT FACTOR 2018: 1.239

CiteScore 2018: 1.22

SCImago Journal Rank (SJR) 2018: 0.507
Source Normalized Impact per Paper (SNIP) 2018: 0.562

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Volume 29, Issue 4


Efficacy and safety of a single monthly dose of cholecalciferol in healthy school children

Mohammad Shafi Kuchay / Ganesh Sudhakar Jevalikar / Ambrish Mithal / Sunil Kumar Mishra / Navin Dang
Published Online: 2015-09-03 | DOI: https://doi.org/10.1515/jpem-2015-0187


Background: This study aimed to evaluate the efficacy and safety of a single monthly dose of cholecalciferol in healthy school children.

Methods: A total of 118 children of class VI of a residential school were selected to receive vitamin D supplementation in the form of oral cholecalciferol 60,000 IU monthly. Serum calcium and 25-hydroxyvitamin D (25OHD) levels were estimated at 0 and 12 months. The proportion of subjects achieving vitamin D sufficiency was assessed.

Results: The mean 25OHD levels increased significantly from 12.04±5.27 ng/mL at baseline to 32.6±7.05 ng/mL after 12 months of supplementation (p<0.001). None developed hypercalcemia.

Conclusions: Vitamin D supplementation in the doses of 60,000 IU monthly is a reasonable, safe and cost-effective regimen for children to attain and maintain vitamin D sufficiency.

Keywords: dosage; India; supplementation; vitamin D


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About the article

Corresponding author: Mohammad Shafi Kuchay, Consultant, Division of Endocrinology and Diabetes, Medanta-The Medicity, Gurgaon 122001, Haryana, India, Phone: +91 9717390365, E-mail:

Received: 2015-05-06

Accepted: 2015-07-27

Published Online: 2015-09-03

Published in Print: 2016-04-01

Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 29, Issue 4, Pages 413–416, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem-2015-0187.

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