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Journal of Pediatric Endocrinology and Metabolism

Editor-in-Chief: Kiess, Wieland

Ed. by Bereket, Abdullah / Darendeliler, Feyza / Dattani, Mehul / Gustafsson, Jan / Luo, Fei Hong / Mericq, Veronica / Toppari, Jorma

IMPACT FACTOR 2018: 1.239

CiteScore 2018: 1.22

SCImago Journal Rank (SJR) 2018: 0.507
Source Normalized Impact per Paper (SNIP) 2018: 0.562

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Volume 29, Issue 7


Propionic acidemia: a Turkish case report of a successful pregnancy, labor and lactation

Neslihan Önenli Mungan
  • Corresponding author
  • Faculty of Medicine, Department of Pediatrics, Cukurova University, 01130, Balcalı, Adana, Turkey
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  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Deniz Kör / Selim Büyükkurt
  • Faculty of Medicine, Departments of Gynecology and Obstetrics, Cukurova University, Adana, Turkey
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Anıl Atmış / Ümran Güleç
  • Faculty of Medicine, Departments of Gynecology and Obstetrics, Cukurova University, Adana, Turkey
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  • De Gruyter OnlineGoogle Scholar
/ Mehmet Satar
Published Online: 2016-04-18 | DOI: https://doi.org/10.1515/jpem-2015-0451


Although propionic acidemia (PA) is a devastating inherited metabolic disease, with early diagnosis and advanced treatment strategies prognosis gets better and girls can survive to child-bearing ages. We share the detailed follow-up data of the pregnancy, successful labor with cesarean section and a healthy baby of a Turkish patient with PA.

Keywords: lactation; metabolic decompensation; organic academia; pregnancy; propionic acidemia (PA)


  • 1.

    Alberola TM, Bautista-Llacer R, Vendrell X, Garcia-Mengual E, Pardo M, et al. Case report: birth of healthy twins after preimplantation genetic diagnosis of propionic academia. J Assist Reprod Genet 2011;28:211–6.Google Scholar

  • 2.

    Chapman KA, Summar ML. Propionic acidemia consensus conference summary. Mol Genet Metab 2012;105:3–4.Google Scholar

  • 3.

    Van Calcar SC, Harding CO, Davidson SR, Barness LA, Wolff JA. Case reports of successful pregnancy in women with maple syrup urine disease and propioni cacidemia. Am J Med Genet 1992:44;641–6.Google Scholar

  • 4.

    Langendonk JG, Roos JC, Angus L, Williams M, Karstens FP, et al. Aseries of pregnancies in women with inherited metabolic disease. J Inherit Metab Dis 2012;35:419–24.Google Scholar

  • 5.

    Raval DB, Merideth M, Sloan JL, Braverman NE, Conway RL, et al. Methylmalonic academia (MMA) in pregnancy: a case series and literature review. J Inherit Metab Dis 2015;38:839–46.Google Scholar

  • 6.

    Cordero DR, Baker J, Dorinzi D, Toffle R. Ornithine transcarbamylase deficiency in pregnancy. J Inherit Metab Dis 2005;28:237–40.Google Scholar

  • 7.

    Lamb S, Yi Ling Aye C, Murphy E, Mackillop L. Multidisciplinary management of ornithine transcarbamylase (OTC) deficiency in pregnancy: essential to prevent hyperammonemic complications. BMJ Case Reports 2013; doi: 10.1136/bcr-2012-007416.CrossrefGoogle Scholar

  • 8.

    Williams SF, Alvarez JR, Pedro HF, Apuzzio JJ. Glutaric aciduria type II and narcolepsy in pregnancy. Obstet Gynecol 2008;111:522–4.Web of ScienceGoogle Scholar

About the article

Received: 2015-11-25

Accepted: 2016-02-22

Published Online: 2016-04-18

Published in Print: 2016-07-01

Author contributions: All the authors have accepted responsibility for the entire content of this submitted manuscript and approved submission.

Research funding: None declared.

Employment or leadership: None declared.

Honorarium: None declared.

Competing interests: The funding organization(s) played no role in the study design; in the collection, analysis, and interpretation of data; in the writing of the report; or in the decision to submit the report for publication.

Citation Information: Journal of Pediatric Endocrinology and Metabolism, Volume 29, Issue 7, Pages 863–866, ISSN (Online) 2191-0251, ISSN (Print) 0334-018X, DOI: https://doi.org/10.1515/jpem-2015-0451.

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