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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year


IMPACT FACTOR 2016: 1.577
5-year IMPACT FACTOR: 1.705

CiteScore 2016: 1.49

SCImago Journal Rank (SJR) 2015: 0.829
Source Normalized Impact per Paper (SNIP) 2015: 0.808

Online
ISSN
1619-3997
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In This Section
Volume 36, Issue 3 (May 2008)

Issues

Seroprevalence and risk factors associated with herpes simplex virus infection among pregnant women

Victoria Arama
  • 1Department Adults 3 of National Institute of Infectious Diseases “Professor Dr. Matei Bals” Bucharest, Romania
/ Radu Vladareanu
  • 2Department of Obstetrics-Gynecology, Elias University Emergency Hospital, Bucharest, Romania
/ Raluca Mihailescu
  • 3Department Adults 3 of National Institute of Infectious Diseases “Professor Dr. Matei Bals” Bucharest, Romania
/ Adrian Streinu Cercel
  • 4Department Adults 2 of National Institute of Infectious Diseases “Professor Dr. Matei Bals” Bucharest, Romania
/ Carina Mihai
  • 5University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
/ Adriana Hristea
  • 6Department Adults 3 of National Institute of Infectious Diseases “Professor Dr. Matei Bals” Bucharest, Romania
/ Mihaela Iosipenco
  • 7Laboratory of Virology, National Institute of Infectious Diseases “Professor Dr. Matei Bals” Bucharest, Romania
/ Sorin Stefan Arama
  • 8University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
/ Muriel Rabilloud
  • 9Hospices Civils de Lyon, Service de Biostatistique, Lyon, F-69424, France; Université de Lyon Université Lyon I, Villeurbanne, F-69622, France; CNRS; UMR 5558, Laboratoire Biostatistique Santé, Pierre-Bénite, F-69495, France
Published Online: 2008-05-19 | DOI: https://doi.org/10.1515/JPM.2008.046

Abstract

Objectives: To estimate the type-specific seroprevalence and identify the risk factors associated with herpes simplex virus (HSV)-2 infection in pregnant women in Bucharest, Romania.

Methods: A prospective survey was conducted in 452 subjects, aged 15–39 years, at the Elias Hospital, during the years 2004–2005. We evaluated serum IgG anti-bodies to HSV-1 and HSV-2 using the HerpeSelect® ELISA test. All subjects completed an epidemiological questionnaire.

Results: Seroprevalence was 87.3% and 15.1% for HSV-1 and HSV-2, respectively. The risk factors for HSV-2 infection were lower level of education and a greater number of sexual partners. Elementary school and high-school graduates were 6.28 and 2.26 times more exposed than University graduates. Having 2–3 partners and more than three partners was associated with 2.43 and 4.26 times the risk of acquiring HSV-2, compared with having one partner.

Conclusions: In pregnant women, HSV-1 seroprevalence was higher than in Western Europe but similar to that in Eastern Europe. HSV-2 seroprevalence was within European ranges. Both were lower than in the USA. Risk factors for HSV-2 infection may lead to prevention programs.

Keywords: Herpes simplex virus; pregnant women; Romania; seroprevalence

About the article

Corresponding author: Raluca Mihailescu, MD Bd.Unirii 37 Bucharest 030823 Romania Tel.: +40 721 638 343


Received: 2007-11-07

Revised: 2008-01-22

Accepted: 2008-02-05

Published Online: 2008-05-19

Published in Print: 2008-05-01



Citation Information: Journal of Perinatal Medicine, ISSN (Online) 16193997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2008.046. Export Citation

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