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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, MD, FRCOG, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Reiss, Irwin / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year

IMPACT FACTOR 2016: 1.577
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CiteScore 2016: 1.49

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Volume 29, Issue 2 (Apr 2001)


Incidence and birth weight characteristics of twins born to mothers aged 40 years or more compared with 35-39 years old mothers: a population study

Isaac Blickstein / Ran D. Goldman / Ram Mazkereth
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/JPM.2001.016


Objective: To compare the incidence of twin births and their birth weight characteristics in mothers aged ≥ 40 years with those of mothers aged 35–39 years.

Methods: We used a population-based cohort of Israeli twins delivered between 1993–98 to compare birth weight characteristics of 510 and 2102 twin pairs delivered to mothers aged ≥ 40 years (cases) and 35–39 years (controls), respectively.

Results: The incidence of twin mothers aged 40 years or more increased 50% during the study period, ten times more than mothers aged 35–39. There were significantly more nulliparas (P < .001, OR 1.54, 95% CI 1.2, 1.9) and more para ≥ 4 (P< .004, OR 1.38, 95% CI 1.1, 1.7) among older mothers. Irrespective of parity, there were no significant differences between mean twin birth weight, total twin birth weight < 3000 g, 3000–4999 g, and ≥ 5000 g, and frequencies of very low birth weight neonates.

Conclusions: Twin birth at the age of ≥ 40 years is significantly more likely among either nulliparas or para ≥ 4. Birth weight characteristics of twins delivered to mothers aged ≥ 40 years are not different from those delivered to 35–39 years old mothers.

About the article

Published Online: 2005-06-01

Published in Print: 2001-04-05

Citation Information: Journal of Perinatal Medicine, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2001.016.

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