Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, MD, FRCOG, Joachim W.

Ed. by Bancalari, Eduardo / Chappelle, Joseph / Chervenak, Frank A. / D'Addario , Vincenzo / Genc, Mehmet R. / Greenough, Anne / Grunebaum, Amos / Konje, Justin C. / Kurjak M.D., Asim / Romero, Roberto / Zalud, MD PhD, Ivica

IMPACT FACTOR 2018: 1.361
5-year IMPACT FACTOR: 1.578

CiteScore 2018: 1.29

SCImago Journal Rank (SJR) 2018: 0.522
Source Normalized Impact per Paper (SNIP) 2018: 0.602

See all formats and pricing
More options …
Volume 29, Issue 5


Metabolic acidosis, core-peripheral temperature difference and blood pressure response to albumin infusion in hypotensive, very premature infants

Gabriel Dimitriou / Anne Greenough / Jason Mantagos / Sarah Skinner
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/JPM.2001.061


The aim of this study was to assess if albumin infusion in hypotensive, preterm infants improved blood pressure (BP), metabolic acidosis and core peripheral temperature difference, indicating that such infants had been hypovolemic. Thirty-seven infants, median gestational age 27 weeks (range 23–34) were studied. Their mean BP, core-peripheral temperature difference, pH and base deficit prior to and post albumin infusion were compared. Albumin infusion was associated with BP elevation (p < 0.01) and a small reduction in the base deficit (p < 0.01), but no significant changes overall in the pH or peripheral core temperature difference. Similar results were seen if only 34 infants less than or equal to 4 days of age treated for their first episode of hypotension were considered, although in that group there was also a modest rise in pH (p < 0.02). These data suggest clinically relevant hypovolemia is uncommon in hypotensive, preterm ventilated infants and hence volume expanders are inappropriate routine first therapy.

About the article

Published Online: 2005-06-01

Published in Print: 2001-11-02

Citation Information: Journal of Perinatal Medicine, Volume 29, Issue 5, Pages 442–445, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2001.061.

Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Nick Evans
Seminars in Neonatology, 2003, Volume 8, Number 4, Page 315
J J Han, H E Yim, J H Lee, Y K Kim, G Y Jang, B M Choi, K H Yoo, and Y S Hong
Journal of Perinatology, 2009, Volume 29, Number 6, Page 444
R-J Teng, T-J Wu, R Sharma, R D Garrison, and M L Hudak
Journal of Perinatology, 2006, Volume 26, Number 8, Page 471

Comments (0)

Please log in or register to comment.
Log in