Jump to ContentJump to Main Navigation
Show Summary Details

Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Greenough, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Ogata, Edward / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

IMPACT FACTOR increased in 2015: 1.798
Rank 46 out of 120 in category Pediatrics in the 2015 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2014: 0.731
Source Normalized Impact per Paper (SNIP) 2014: 0.687
Impact per Publication (IPP) 2014: 1.483

See all formats and pricing


Select Volume and Issue


Oral nifedipine maintenance therapy after acute intravenous tocolysis in preterm labor

N.C. Sayin / F.G. Varol / P. Balkanli-Kaplan / M. Sayin

Citation Information: Journal of Perinatal Medicine. Volume 32, Issue 3, Pages 220–224, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2004.041, June 2005

Publication History

Published Online:


Aims: Our aim was to evaluate the efficacy of maintenance oral nifedipine in pregnant women initially treated with intravenous ritodrine plus verapamil for preterm labor.

Methods: The study included 73 patients with preterm labor with intact membranes. Patients were randomized to receive either maintenance oral nifedipine therapy (n=37) administered 20 mg every six hours or no treatment (controls, n=36) after discontinuation of acute intravenous tocolysis.

Results: Compared to the control group, the mean±SD time gained from initiation of maintenance therapy to delivery (26.65±18.89 vs. 16.14±12.91 days, p=0.007) and the gestational age at delivery (37.03±2.06 vs. 35.1±3 weeks, p=0.003) were higher in the nifedipine maintenance therapy group. The proportion of patients who required one or more courses of subsequent intravenous therapy and perinatal outcomes were similar in the maintenance therapy and control groups.

Conclusions: The gestational age and time gained from initiation of maintenance therapy to delivery were longer in women receiving oral maintenance tocolysis with nifedipine. However, maintenance therapy did not decrease the recurrence of preterm labor episodes or improve perinatal outcomes.

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Gabriele Saccone, Anju Suhag, and Vincenzo Berghella
American Journal of Obstetrics and Gynecology, 2015, Volume 213, Number 1, Page 16
Emma Parry, Carolien Roos, Peter Stone, Lynsey Hayward, Ben Willem Mol, and Lesley McCowan
Australian and New Zealand Journal of Obstetrics and Gynaecology, 2014, Volume 54, Number 3, Page 231
S. Kamat, P. Veena, and R. Rani
Journal of Obstetrics & Gynaecology, 2014, Volume 34, Number 4, Page 322
S. Carrez and J. Sibiude
Gynécologie Obstétrique & Fertilité, 2013, Volume 41, Number 7-8, Page 465
S.G. Oei
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2006, Volume 126, Number 2, Page 137
Katie M. Groom
Best Practice & Research Clinical Obstetrics & Gynaecology, 2007, Volume 21, Number 5, Page 843
M. Pato, C. Varillas, P. Frade, D. Gómez-Sánchez, L. Castro-Vilar, and S. Blanco
Clínica e Investigación en Ginecología y Obstetricia, 2011, Volume 38, Number 3, Page 109
Agustín Conde-Agudelo, Roberto Romero, and Juan Pedro Kusanovic
American Journal of Obstetrics and Gynecology, 2011, Volume 204, Number 2, Page 134.e1
Herman P. Geijn, Joris E. Lenglet, and Annemieke C. Bolte
BJOG: An International Journal of Obstetrics & Gynaecology, 2005, Volume 112, Page 79
N. Cenk Sayin, Sezer Arda, Füsun G. Varol, and Necdet Süt
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2010, Volume 152, Number 1, Page 50
Deirdre J. Lyell, Kristin M. Pullen, Jana Mannan, Usha Chitkara, Maurice L. Druzin, Aaron B. Caughey, and Yasser Y. El-Sayed
Obstetrics & Gynecology, 2008, Volume 112, Number 6, Page 1221
Y Jacquemyn
BJOG: An International Journal of Obstetrics & Gynaecology, 2006, Volume 113, Page 78
N. Cenk Sayin, Hasan A. Inal, and Füsun G. Varol
Archives of Gynecology and Obstetrics, 2008, Volume 278, Number 6, Page 573

Comments (0)

Please log in or register to comment.