Jump to ContentJump to Main Navigation
Show Summary Details
In This Section

Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year

IMPACT FACTOR 2016: 1.577
5-year IMPACT FACTOR: 1.705

CiteScore 2016: 1.49

SCImago Journal Rank (SJR) 2015: 0.829
Source Normalized Impact per Paper (SNIP) 2015: 0.808

See all formats and pricing
In This Section
Volume 32, Issue 3 (May 2004)


Amniotic fluid and cord plasma erythropoietin levels in pregnancies complicated by preeclampsia, pregnancy-induced hypertension and chronic hypertension

K.A. Teramo / V.K. Hiilesmaa / R. Schwartz / G.K. Clemons / J.A. Widness
Published Online: 2005-06-01 | DOI: https://doi.org/10.1515/JPM.2004.045


Aims: The purpose of the present study was to compare fetal and neonatal outcomes with amniotic fluid erythropoietin (EPO) levels obtained in the antepartum period in pregnancies complicated by preeclampsia, pregnancy-induced hypertension or chronic hypertension.

Methods: Erythropoietin concentrations were measured in amniotic fluid within 2 days before delivery and in cord blood at birth in 75 hypertensive women and in 23 healthy controls delivered by cesarean section before labor contractions. Erythropoietin levels did not influence clinical decisions.

Results: Amniotic fluid erythropoietin levels correlated highly significantly with cord plasma EPO levels and were significantly higher in pregnancies complicated by hypertension than in control pregnancies. Umbilical arterial pH, acid-base and blood gas values at birth were not different from controls. Both cord plasma and amniotic fluid erythropoietin levels correlated with cord blood pH, acidbase and blood gas values at birth in the study group. Newborn infants admitted to the newborn intensive care unit had significantly higher fetal erythropoietin levels and were more acidotic, hypoxemic and hypoglycemic than infants admitted to the normal care nursery.

Conclusions: Our findings suggest that elevated amniotic fluid erythropoietin levels are markers of chronic or subchronic fetal hypoxia and are associated with neonatal morbidity in pregnancies complicated by hypertension.

About the article

Published Online: 2005-06-01

Published in Print: 2004-05-05

Citation Information: Journal of Perinatal Medicine, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2004.045. Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Laura Seikku, Leena Rahkonen, Minna Tikkanen, Esa Hämäläinen, Petri Rahkonen, Sture Andersson, Kari Teramo, Jorma Paavonen, and Vedran Stefanovic
Acta Obstetricia et Gynecologica Scandinavica, 2015, Volume 94, Number 3, Page 288
S. Sohlberg, A. Mulic-Lutvica, P. Lindgren, F. Ortiz-Nieto, A.-K. Wikström, and J. Wikström
Placenta, 2014, Volume 35, Number 3, Page 202
Zeljko Mikovic, Vesna Mandic, Vladimir Parovic, Mirjana Bogavac, and Natasa Simin
Journal of Maternal-Fetal and Neonatal Medicine, 2014, Volume 27, Number 11, Page 1134
Máximo Vento and Kari Teramo
Seminars in Fetal and Neonatal Medicine, 2013, Volume 18, Number 6, Page 324
Martha C. Tissot van Patot, German Ebensperger, Max Gassmann, and Aníbal J. Llanos
High Altitude Medicine & Biology, 2012, Volume 13, Number 3, Page 176
Seong-Jo Yun, Purevjargal Naidansuren, Bo-Woong Sim, Jong-Ju Park, Cha-Won Park, Tseeleema Nanjidsuren, Myung-Hwa Kang, Sue-Yun Hwang, Jong-Taek Yoon, and Kwan-Sik Min
Reproductive Biology and Endocrinology, 2012, Volume 10, Number 1, Page 6
Seul Ki Lim and Soo Hyun Park
Laboratory Animal Research, 2011, Volume 27, Number 3, Page 245
Bettina Toth, Anja Fischl, Christoph Scholz, Susanne Kunze, Klaus Friese, and Udo Jeschke
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2008, Volume 140, Number 2, Page 192
Anna Girsen, Kaarin Mäkikallio, Vilho Hiilesmaa, Esa Hämäläinen, Kari Teramo, and Juha Räsänen
American Journal of Obstetrics and Gynecology, 2007, Volume 196, Number 5, Page 467.e1
Antonette T. Dulay, Irina A. Buhimschi, Guomao Zhao, Guoyang Luo, Sonya Abdel-Razeq, Michael Cackovic, Victor A. Rosenberg, Christian M. Pettker, Stephen F. Thung, Mert O. Bahtiyar, Vineet Bhandari, and Catalin S. Buhimschi
American Journal of Obstetrics and Gynecology, 2008, Volume 198, Number 4, Page 426.e1
Andrée Gruslin and Brigitte Lemyre
Best Practice & Research Clinical Obstetrics & Gynaecology, 2011, Volume 25, Number 4, Page 491
Robert A. Brace, Cecilia Y. Cheung, Lowell E. Davis, Robert Gagnon, Richard Harding, and John A. Widness
American Journal of Obstetrics and Gynecology, 2006, Volume 195, Number 1, Page 246
Kari A. Teramo
Best Practice & Research Clinical Endocrinology & Metabolism, 2010, Volume 24, Number 4, Page 663
Yaron Haimovich, Jessica Ascher-Landsberg, Fuad Azem, Dror Mandel, Francis B. Mimouni, and Ariel Many
Journal of Perinatal Medicine, 2011, Volume 39, Number 3
Tae Hwan Kil, Ji Yeon Han, Jun Bum Kim, Gyeong Ok Ko, Young Hyeok Lee, Kil Young Kim, and Jae Woo Lim
Korean Journal of Pediatrics, 2011, Volume 54, Number 2, Page 69
Sabine Gack, Alexander Marmé, Frederik Marmé, Gunnar Wrobel, Birgitta Vonderstraß, Gunther Bastert, Peter Lichter, Peter Angel, and Marina Schorpp-Kistner
Journal of Molecular Medicine, 2005, Volume 83, Number 11, Page 887
Lawrence C. Tsen
Anesthesiology, 2005, Volume 102, Number 3, Page 672
K. Teramo, M. A. Kari, M. Eronen, H. Markkanen, and V. Hiilesmaa
Diabetologia, 2004, Volume 47, Number 10, Page 1695

Comments (0)

Please log in or register to comment.
Log in