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Licensed Unlicensed Requires Authentication Published by De Gruyter July 5, 2005

Thrombocytopoiesis in healthy term newborns

  • Alicja Wasiluk

Abstract

Aims: Thrombocytopoiesis was investigated in term newborns determining thrombopoietin (TPO), reticulated platelets (PLRET) and blood platelets (PLT) in relation to gender.

Patients and methods: The study was undertaken on 72 healthy term newborns, 33 girls and 39 boys. They fitted all criteria for healthy term newborns. Blood was collected from the umbilical vein immediately after cutting the umbilical cord. The evaluation of thrombocytopoiesis was performed by the following methods: TPO–Quantikine human TPO kit, PLRET– Retic-Count kit, PLT– Advia™ 120 hematology System.

Results: Concentrations of TPO and percentages of reticulated platelets were greater in the female group than in the male group. The changes were not statistically significant, perhaps as a result of the very wide range of parameters tested. The blood platelet count was higher in female newborns than in male newborns, P<0.001.

Conclusion: The data may indicate that thrombocytopoiesis is more active in female than in male newborns.

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Corresponding author: Alicja Wasiluk, M.D., Department of Neonatology, Białystok ul. MC. Skłodowskiej 24 a, Poland. Tel.: +48 85 74 68 338, +48 85 74 47 867 Fax: +48 85 74 68 663 E-mail:

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Published Online: 2005-07-05
Published in Print: 2005-05-01

© by Walter de Gruyter Berlin New York

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