Jump to ContentJump to Main Navigation
Show Summary Details
In This Section

Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year

IMPACT FACTOR 2016: 1.577
5-year IMPACT FACTOR: 1.705

CiteScore 2016: 1.49

SCImago Journal Rank (SJR) 2015: 0.829
Source Normalized Impact per Paper (SNIP) 2015: 0.808

See all formats and pricing
In This Section
Volume 36, Issue 2 (Mar 2008)


Retrospective audit of outcome of regional anesthesia for delivery in women with thrombocytopenia

Kyra Bernstein
  • 1Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel
/ Abigail Baer
  • 2Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel
/ Martine Pollack
  • 3Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel
/ Dov Sebrow
  • 4Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel
/ Deborah Elstein
  • 5Gaucher Clinic, Shaare Zedek Medical Center, Jerusalem, Israel
/ Alexander Ioscovich
  • 6Department of Anesthesiology, Shaare Zedek Medical Center, Jerusalem, Israel
Published Online: 2008-03-10 | DOI: https://doi.org/10.1515/JPM.2008.020


Regional anesthesia for pain at delivery in the presence of maternal thrombocytopenia is a clinical dilemma. We reviewed 10,369 obstetric cases (12 months) from our tertiery center. Generally, hemodilution of pregnancy does not result in thrombocyte counts of <150,000/mm3 at delivery. A total of 166 births (1.6%) were recorded in women with thrombocytes <150,000/mm3 at delivery. Parturients with >150,000/mm3 at week 36 were separated post hoc (n=35; 21%) and the remaining parturients were divided as having <100,000/mm3 (n=30; 18%) or 101,000–150,000/mm3 (n=101; 60.5%). Epidural or spinal anesthesia was administered to 30% women with <100,000/mm3 whereas 56% women with >101,000/mm3 received these options (P=0.003). A total of 13.9% of parturients with trimester-long thrombocytopenia required blood products; 10/23 (43.5%) parturients undergoing cesarean section also required blood products (P=0.000). Four of six babies with Apgar scores of ≤7 at 1-min were born to women with platelets <100,000/mm3 (P=0.009). There were no statistically significant differences in mean birth weights. Women with thrombocytes <150,000/mm3 at birth but within the normal range at week 36 were more likely multiparas (P=0.001). We conclude that a difference in maternal and neonatal outcomes exists between mothers who were thrombocytopenic only at delivery compared to those with trimester-long thrombocytopenia, with the latter mothers and babies having more adverse events.

Keywords: Apgar scores; blood products; delivery; maternal outcome; neonatal outcome; regional anesthesia; thrombocytopenia

About the article

Corresponding author: Deborah Elstein, PhD Gaucher Clinic Shaare Zedek Medical Center P.O. Box 3235 Jerusalem 91031 Israel Tel.: +972-2-655-5093 Fax: +972-2-651-7979

Received: 2007-07-01

Revised: 2007-11-05

Accepted: 2007-11-24

Published Online: 2008-03-10

Published in Print: 2008-03-01

Citation Information: Journal of Perinatal Medicine, ISSN (Online) 16193997, ISSN (Print) 03005577, DOI: https://doi.org/10.1515/JPM.2008.020. Export Citation

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

Daniel Dikman, Deborah Elstein, Gal Schtrechman Levi, Sorina Granovsky-Grisaru, Arnon Samueloff, Yaacov Gozal, and Alexander Ioscovich
Journal of Maternal-Fetal and Neonatal Medicine, 2014, Volume 27, Number 6, Page 597
Yvonne A. Dobbenga-Rhodes
AORN Journal, 2009, Volume 89, Number 6, Page 1079
Joost J. Van Veen, Timothy J. Nokes, and Mike Makris
British Journal of Haematology, 2010, Volume 148, Number 1, Page 15

Comments (0)

Please log in or register to comment.
Log in