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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Ogata, Edward / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

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Volume 36, Issue 4 (Jul 2008)


Intrauterine restriction (IUGR)

Giampaolo Mandruzzato
  • 1Department of Obstetrics and Gynecology, Istituto per l'Infanzia, Burlo Garofolo, Trieste, Italy
/ Aris Antsaklis
  • 2Department Obstetrics and Gynecology, Alexandra Hospital, University of Athens, Greece
/ Francesc Botet
  • 3Neonatology Service, Hospital Clinic, Institut Clinic, Ostetrica, Ginecologia, Neonatologia, Universidad de Barcelona, Spain
/ Frank A. Chervenak
  • 4Weill Medical College of Cornell University, New York, USA and New York Hospital, Queens, New York, USA
/ Francisc Figueras
  • 5Fetal medicine Service, Hospital Clinic, Institut Clinic Obstetricia, Ginecologia, Neonatologia, Universidada de Barcelona, Spain
/ Amos Grunebaum
  • 6Weill Medical College of Cornell University, New York, USA and New York Hospital, Queens, New York, USA
/ Bienve Puerto
  • 7Fetal medicine Service, Hospital Clinic, Institut Clinic Obstetricia, Ginecologia, Neonatologia, Universidada de Barcelona, Spain
/ Daniel Skupski
  • 8Weill Medical College of Cornell University, New York, USA and New York Hospital, Queens, New York, USA and New York Hospital, Queens, New York, USA
/ Milan Stanojevic
  • 9Department Obstetrics and Gynecology, Medical School of University of Zagreb, Sveti Duh General Hospital, Zagreb, Croatia
Published Online: 2008-05-19 | DOI: https://doi.org/10.1515/JPM.2008.050


Perinatal mortality and morbidity is markedly increased in intrauterine growth restricted (IUGR) fetuses. Prenatal identification of IUGR is the first step in clinical management. For that purpose a uniform definition and criteria are required. The etiology of IUGR is multifactorial and whenever possible it should be assessed. When the cause is of placental origin, it is possible to identify the affected fetuses. The major complication is chronic fetal hypoxemia. By monitoring the changes of fetal vital functions it is thus possible to improve both management and outcome. The timing of delivery is crucial but the optimal management scheme has not yet been identified. When IUGR is identified at very early gestational ages, serial assessments of the risk of continuing the in utero fetal life under adverse conditions versus the risks of the prematurity should be performed. Delivery of IUGR fetuses should take place in centers where appropriate neonatal assistance can be provided. Careful monitoring of the IUGR fetus during labor is crucial as the IUGR fetus can quickly decompensate once uterine contractions have started.

Keywords: Fetal assessment; IURG; neonatal outcome; SGA

About the article

Corresponding author: Giampaolo Mandruzzato, MD Via del Lazzaretto vecchio 9 34132 Trieste Italy

Published Online: 2008-05-19

Published Online: 2008-05-24

Published in Print: 2008-07-01

Citation Information: Journal of Perinatal Medicine, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2008.050. Export Citation

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