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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, MD, FRCOG, Joachim W.

Ed. by Bancalari, Eduardo / Chappelle, Joseph / Chervenak, Frank A. / D'Addario , Vincenzo / Genc, Mehmet R. / Greenough, Anne / Grunebaum, Amos / Konje, Justin C. / Kurjak M.D., Asim / Romero, Roberto / Zalud, MD PhD, Ivica

IMPACT FACTOR 2018: 1.361
5-year IMPACT FACTOR: 1.578

CiteScore 2018: 1.29

SCImago Journal Rank (SJR) 2018: 0.522
Source Normalized Impact per Paper (SNIP) 2018: 0.602

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Volume 37, Issue 5


Towards new diagnostic criteria for diagnosing GDM – the HAPO study

Eran Hadar
  • Perinatal Division, Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah-Tiqva, Israel
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Jeremy Oats / Moshe Hod
  • Perinatal Division, Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah-Tiqva, Israel
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar


Gestational diabetes mellitus (GDM) is defined as a carbohydrate intolerance, with onset or first recognition during pregnancy. The prevalence of GDM, and the occurrence of related complications, depends upon the definition of normal glucose values during gestation. The diagnostic criteria for GDM are controversial mainly because they lack correlation to outcome, be it maternal or perinatal. To date, there are no risk based guidelines to make the diagnosis of GDM and determine practice guidelines that are extrapolated from perinatal and maternal outcome and endpoints. To answer some of the above-mentioned controversies, the hyperglycemia and adverse pregnancy outcome study (HAPO) was planned and executed. This review outlines the results of the HAPO study, which demonstrates that fasting glucose levels and post 75 g OGTT are correlated to maternal, perinatal and neonatal outcomes. It is anticipated that the international recommendation for GDM diagnosis, will be shortly published.

Keywords: Gestational diabetes mellitus; hyperglycemia and adverse pregnancy outcome (HAPO) study

About the article

Corresponding author: Prof. Moshe Hod, MD Perinatal Division, Helen Schneider Hospital for Women Rabin Medical Center Sackler Faculty of Medicine Tel Aviv University Petah-Tiqva 49100 Israel Tel.: +972-3-9377400

Received: 2009-05-06

Revised: 2009-07-21

Accepted: 2009-07-23

Published in Print: 2009-09-01

Citation Information: Journal of Perinatal Medicine, Volume 37, Issue 5, Pages 447–449, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/JPM.2009.114.

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