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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Ogata, Edward / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

IMPACT FACTOR increased in 2015: 1.798
Rank 46 out of 120 in category Pediatrics in the 2015 Thomson Reuters Journal Citation Report/Science Edition

SCImago Journal Rank (SJR) 2014: 0.731
Source Normalized Impact per Paper (SNIP) 2014: 0.687
Impact per Publication (IPP) 2014: 1.483

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Pregnancy and delivery outcomes of HIV infected women in Switzerland 2003–2008

Karoline Aebi-Popp1 / Olav Lapaire1 / Tracy R. Glass2 / Louise Vilén3 / Christoph Rudin4 / Luigia Elzi5 / Mannel Battegay5 / Olivia Keiser6 / Begona Martinez de Tejada7 / Irene M. Hoesli1 / The Swiss Mother and Child HIV Cohort Study

1Division of Obstetrics and Gynaecology, University Hospital Basel, Switzerland

2Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Switzerland

3Institute for Psychology, University Bern, Switzerland

4Division of Infectious Diseases, University Children's Hospital, Basel, Switzerland

5Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Switzerland

6Institute for Social and Preventive Medicine, Bern, Switzerland

7Division of Obstetrics and Gynaecology, University Hospital Geneva, Switzerland

Corresponding author: K. Aebi-Popp, MD Department of Obstetrics and Gynaecology University Hospital Basel Spitalstrasse 21 CH-4031 Basel Switzerland Tel.: +41 61 265 2525 Fax: +41 61 265 9198

Citation Information: Journal of Perinatal Medicine. Volume 38, Issue 4, Pages 353–358, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm.2010.052, February 2010

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Objective: Rates of vertical HIV transmission between mother and child are low, allowing many HIV positive women to have children with near impunity. In this study, data from the Swiss Mother and Child HIV Cohort Study were used to describe maternal characteristics and their association with pregnancy outcomes in HIV positive women.

Study design: HIV positive women were followed prospectively during their pregnancies and deliveries by anonymous questionnaires between January 2003 and October 2008. Adverse pregnancy outcomes included preterm delivery, preeclampsia and gestational diabetes mellitus.

Results: This study included 266 HIV positive women, of which 67 (25.2%) were first diagnosed with HIV during pregnancy. Thirty percent (n=80) of the women had pregnancy complications after 24 weeks of gestation. Preterm delivery was noted in 72 (27%) patients. Other complications included preeclampsia (n=7; 2.6%) and gestational diabetes (n=7; 2.6%). Older maternal age was the only risk factor associated with adverse pregnancy outcomes (adjusted odds ratio: 1.06, 95% confidence interval 1.01–1.12, P=0.02).

Conclusions: HIV positive women, especially with advanced maternal age, have high-risk pregnancies and should be monitored as in an interdisciplinary setting. The preponderance of initial HIV diagnosis during pregnancy confirms the importance of HIV screening in pregnant women.

Keywords: HIV; maternal age; pregnancy; preterm delivery

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