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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Ogata, Edward / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

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Risk groups and maternal-neonatal complications of preeclampsia – Current results from the national German Perinatal Quality Registry

1, 2, a / Nele Freerksen3, a / Holger Maul4, a / Silke Roehrig2 / Burkhard Fischer5 / Birgit Hoeft1, a

1Mannheim Institute of Public Health, Social and Preventive Medicine (MIPH) Mannheim Medical Faculty, Heidelberg University, Ludolf-Krehl-Str. 7-11, D-68167 Mannheim, Germany

2Competence Center for Social Medicine and Occupational Health Promotion, Heidelberg University, Ludolf-Krehl-Str. 7-11, D-68167 Mannheim, Germany

3University Women’s Hospital of the RWTH Aachen, Aachen University, Pauwelsstr. 30, D-52074 Aachen, Germany

4Women’s Hospital, Katholisches Marienkrankenhaus, Alfredstr. 9, D-22087 Hamburg, Germany

5German Federal Agency for Quality Assurance gGmbH, Düsseldorf, Kanzlerstr. 4, D-40472 Düsseldorf, Germany

aAuthors contributed to this paper equally.

Corresponding author: Sven Schneider, Prof., Dr., MA Mannheim Institute for Public Health Social and Preventive Medicine (MIPH) Medical Faculty Mannheim Heidelberg University Ludolf-Krehl-Str 7-11 D-68167 Mannheim Germany Tel.: +49-621-383-9917 Fax: +49-621-383-9920

Citation Information: Journal of Perinatal Medicine. Volume 39, Issue 3, Pages 257–265, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm.2011.010, February 2011

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Aims: We investigated risk factors and neonatal outcomes of preeclampsia.

Methods: We analyzed data of the German Perinatal Quality Registry 2006 that contains the complete national birth cohort of 668,085 newborn infants and 647,392 mothers from 917 German obstetric clinics.

Results: The prevalence of preeclampsia in 2006 was at 2.31%. Higher maternal age, gestational diabetes, no previous as well as multiple births, pre-pregnancy obesity and above-average weight gain during pregnancy were significantly associated with preeclampsia. A positive relationship between social burden (e.g., low social status, psychosocial stress) and the risk of preeclampsia appeared. Smoking appeared to be negatively correlated. Neonatal complications associated with preeclampsia in the study were small babies, acute respiratory distress syndrome, postpartum neonatal hypoglycemia and low Apgar scores. We did not observe an increased rate of stillbirths with preeclampsia pregnancies.

Conclusions: Further studies and interventions regarding prenatal care should not focus only on how better diagnostic and treatment procedures can be implemented but also on how these diagnostic and treatment procedures can reach high-risk groups.

Keywords: Abnormalities; gestational diabetes; gestosis; hypertension; preeclampsia; pregnancy complications; proteinuria; risk factors

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