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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year


IMPACT FACTOR 2016: 1.577
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Online
ISSN
1619-3997
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Volume 39, Issue 3 (May 2011)

Issues

Predicting mortality in infants with persistent pulmonary hypertension of the newborn with the Score for Neonatal Acute Physiology-Version II (SNAP-II) in Thai neonates

Narongsak Nakwan
  • Neonatal Intensive Care Unit, Hat Yai Medical Education Center, Hat Yai Hospital, Songkhla, Thailand
  • Department of Pediatrics, Hat Yai Medical Education Center, Hat Yai Hospital, Songkhla, Thailand
  • Email:
/ Narongwit Nakwan
  • Department of Medicine, Hat Yai Medical Education Center, Hat Yai Hospital, Songkhla, Thailand
/ Jeerawan Wannaro
  • Department of Pediatrics, Hat Yai Medical Education Center, Hat Yai Hospital, Songkhla, Thailand
Published Online: 2011-04-14 | DOI: https://doi.org/10.1515/jpm.2011.011

Abstract

Aim: To evaluate the ability of the Score for Neonatal Acute Physiology-Version II (SNAP-II) to predict mortality in infants with persistent pulmonary hypertension of the newborn (PPHN).

Methods: A prospective cohort study of 41 infants with PPHN admitted to our neonatal intensive care unit between June 2008 and March 2010, who underwent a SNAP-II test within 12 h of admission.

Results: Of the 41 infants, 14 died (34.1%) and 27 survived (65.9%). The SNAP-II scores were significantly higher in infants who died (50.1±18.5 vs. 35.7±16.8, P=0.02). Each point increase in the SNAP score increased the odds of mortality by 1.04 [95% confidence interval (CI) 1.01–1.07, P<0.01]. Infants who had a SNAP-II score of ≥43 had the greatest mortality risk with an odds ratio (OR) of 10.00 (95% CI 1.03–97.50). The SNAP-II model showed moderate discrimination in predicting mortality with a result of 0.72 (95% CI 0.56–0.88) under the receiver operating characteristic curve. The lowest blood pressure, lowest PaO2/FIO2 ratio, and urine output within the first 12 h of admission were also independently found to be good predictors of an increased risk for death.

Conclusion: The SNAP-II scoring system significantly predicted mortality. PPHN infants with a SNAP-II score of ≥43 had the greatest mortality risk.

Keywords: Neonatal mortality; persistent pulmonary hypertension of the newborn; predictive value of tests; Score for Neonatal Acute Physiology-Version II; severity of illness index

About the article

Corresponding author: Narongsak Nakwan, MD Neonatal Intensive Care Unit Department of Pediatrics Hat Yai Medical Education Center Hat Yai Hospital Songkhla 90110 Thailand Tel.: +66 81 8980546 Fax: +66 74 273161


Received: 2010-08-25

Revised: 2010-10-06

Accepted: 2010-10-21

Published Online: 2011-04-14

Published Online: 2011-04-14

Published in Print: 2011-05-01


Citation Information: Journal of Perinatal Medicine, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm.2011.011.

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