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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, MD, FRCOG, Joachim W.

Ed. by Bancalari, Eduardo / Chappelle, Joseph / Chervenak, Frank A. / D'Addario , Vincenzo / Genc, Mehmet R. / Greenough, Anne / Grunebaum, Amos / Konje, Justin C. / Kurjak M.D., Asim / Romero, Roberto / Zalud, MD PhD, Ivica

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1619-3997
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Volume 39, Issue 3

Issues

Listeriosis in human pregnancy: a systematic review

Ronald F. Lamont
  • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland and Detroit, MI, USA
  • Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
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/ Jack Sobel
  • Department of Infectious Diseases, Wayne State University School of Medicine, Detroit, MI, USA
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/ Shali Mazaki-Tovi
  • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland and Detroit, MI, USA
  • Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
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/ Juan Pedro Kusanovic
  • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland and Detroit, MI, USA
  • Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
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/ Edi Vaisbuch
  • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland and Detroit, MI, USA
  • Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
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/ Sun Kwon Kim / Niels Uldbjerg / Roberto Romero
  • Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, Maryland and Detroit, MI, USA
  • Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
  • Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA
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Published Online: 2011-04-26 | DOI: https://doi.org/10.1515/jpm.2011.035

Abstract

Listeria is commonly found in processed and prepared foods and listeriosis is associated with high morbidity and mortality. Preventative measures are well prescribed and monitoring and voluntary recall of contaminated products has resulted in a 44% reduction in the prevalence of perinatal listeriosis in the USA. Pregnant women are at high risk for listeriosis, but symptoms are non-specific and diagnosis is difficult. The intracellular life-cycle of Listeria protects the bacterium from host innate and adaptive immune responses. Antibiotic treatment requires agents able to penetrate, distribute, and remain stable within host cells. Prolonged use of high-dose ampicillin can significantly improve neonatal outcome.

Keywords: Epidemics; foodborne; infection; Listeria monocytogenes; Listeriosis; neonate; newborn; pregnancy

About the article

Corresponding authors: Ronald F. Lamont, BSc, MB, ChB, MD, FRCOG and Roberto Romero, MD Perinatology Research Branch, NICHD, NIH, DHHS Wayne State University/Hutzel Women’s Hospital 3990 John R, Box 4 Detroit, MI 48201, USA Tel.: +1 (313) 993-2700 Fax: +1 (313) 993-2694


Received: 2010-11-11

Revised: 2011-02-09

Accepted: 2011-02-11

Published Online: 2011-04-26

Published in Print: 2011-05-01


Citation Information: Journal of Perinatal Medicine, Volume 39, Issue 3, Pages 227–236, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm.2011.035.

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