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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, MD, FRCOG, Joachim W.

Ed. by Bancalari, Eduardo / Chappelle, Joseph / Chervenak, Frank A. / D'Addario , Vincenzo / Genc, Mehmet R. / Greenough, Anne / Grunebaum, Amos / Konje, Justin C. / Kurjak M.D., Asim / Romero, Roberto / Zalud, MD PhD, Ivica

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Volume 41, Issue 4


Maternal and fetal adropin levels in gestational diabetes mellitus

Ebru Celik
  • Corresponding author
  • Department of Obstetrics and Gynecology, TurgutOzal Medical Center, Inonu University School of Medicine, 44315, Malatya, Turkey
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ercan Yilmaz / Onder Celik / Mustafa Ulas / Ilgin Turkcuoglu / Abdullah Karaer / Yavuz Simsek / Yagmur Minareci / Suleyman Aydin
Published Online: 2013-01-09 | DOI: https://doi.org/10.1515/jpm-2012-0227


Aim: To evaluate maternal and cord blood serum adropin concentrations in pregnant women with gestational diabetes mellitus (GDM).

Study design: Twenty pregnant women with GDM and 20 gestational age-matched healthy pregnant women participated in the study. Maternal serum and cord blood adropin levels were assessed using an enzyme immunosorbent assay, at the time of birth. The relation of maternal serum and cord blood adropin levels with metabolic parameters were also assessed.

Results: The mean maternal and cord serum adropin in the GDM group were significantly lower than those of the control women (P=0.01 and P<0.001, respectively). Maternal serum adropin levels did not correlate with either fetal serum adropin levels or maternal metabolic values.

Conclusion: The data suggest that low adropin levels may contribute to the underlying pathogenesis of GDM.

Keywords: Adropin; cord blood; gestational diabetes mellitus; glucose; homeostasis model of assessment – insulin resistance (HOMA-IR)


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About the article

Corresponding author: Ebru Celik, MD, Department of Obstetrics and Gynecology, TurgutOzal Medical Center, Inonu University School of Medicine, 44315, Malatya, Turkey, Tel.: +90 532 603 5151, Fax: +90 422 3410660

Received: 2012-09-19

Accepted: 2012-12-03

Published Online: 2013-01-09

Published in Print: 2013-07-01

Citation Information: Journal of Perinatal Medicine, Volume 41, Issue 4, Pages 375–380, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm-2012-0227.

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