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Journal of Perinatal Medicine

Official Journal of the World Association of Perinatal Medicine

Editor-in-Chief: Dudenhausen, Joachim W.

Editorial Board Member: / Bancalari, Eduardo / Milner, Anne / Genc, Mehmet R. / Chervenak, Frank A. / Chappelle, Joseph / Bergmann, Renate L. / Bernardes, J.F. / Bevilacqua, G. / Blickstein, Isaac / Cabero Roura, Luis / Carbonell-Estrany, Xavier / Carrera, Jose M. / D`Addario, Vincenzo / D'Alton, MD, Mary E. / Dimitrou, G. / Grunebaum, Amos / Hentschel, Roland / Köpcke, W. / Kawabata, Ichiro / Keirse, Marc J.N.C. / Kurjak M.D., Asim / Lee, Ben H. / Levene, Malcolm / Lockwood, Charles J. / Marsal, Karel / Makatsariya, Alexander / Nishida, Hiroshi / Ogata, Edward / Papp, Zoltán / Pejaver, Ranjan Kumar / Pooh, Ritsuko K. / Romero, Roberto / Saugstad, Ola D. / Schenker, Joseph G. / Sen, Cihat / Seri, Istvan / Vetter, Klaus / Winn, Hung N. / Young, Bruce K. / Zimmermann, Roland

9 Issues per year


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ISSN
1619-3997
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Volume 42, Issue 3 (May 2014)

Issues

Diet or medically treated gestational diabetes: is there any difference for obstetrical and neonatal complications? A French cohort study

Audrey Blachier
  • Département d’information médicale, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
/ Corinne Alberti
  • Unité d’épidémiologie clinique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris and Université Paris 7 Denis Diderot, 48 Boulevard Sérurier, 75019, Paris, France
  • Université Paris Diderot, Sorbonne Paris Cité, Unité d’Épidémiologie Clinique, Paris, France
  • INSERM, CIE 5, Paris, France
/ Diane Korb
  • Université Paris 7 Denis Diderot, UFR de Médecine, Paris, France
  • Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
/ Thomas Schmitz
  • Université Paris 7 Denis Diderot, UFR de Médecine, Paris, France
  • Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
/ Vexiau Patrick
  • Service d’endocrinologie et de diabétologie, Hôpital Saint Louis, Assistance Publique-Hôpitaux de Paris, 1 avenue Claude-Vellefaux, 75010, Paris, France
/ Boissinot Christine
  • Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
/ Jean-François Oury
  • Université Paris 7 Denis Diderot, UFR de Médecine, Paris, France
  • Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
/ Olivier Sibony
  • Corresponding author
  • Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019, Paris, France
  • Email:
Published Online: 2013-11-16 | DOI: https://doi.org/10.1515/jpm-2013-0079

Abstract

Objective: The aim of the present study was to determine specific obstetrical and neonatal complications associated with diet-treated gestational diabetes (DTGD) and medically treated gestational diabetes (MTGD).

Methods: This is a prospective cohort study of women followed in the Robert Debré Hospital (France, Paris) and who have given birth between 1 January, 2004, and 19 November, 2010. Clinical, biological, maternal and neonatal data were reported in the maternity database. Associations between obstetrical and neonatal complications and gestational diabetes were evaluated by estimating odd ratios (ORs) and their 95% CIs, using a logistic regression model.

Results: 16,244 pregnancies were included in the study. 1515 (9.3%) women had gestational diabetes: 1108 (7.3%) had DTGD, 243 (1.7%) had MTGD. After full adjustment, MTGD was associated with an increased risk of nonscheduled cesarean (ORnonscheduled=2.3; 95% CI: 1.6–3.3; P<0.001) while DTGD was not (ORnonscheduled=1.0; 95% CI: 0.8–1.3; P<0.96). Clinical macrosomia was positively associated with DTGD (OR=2; 95% CI: 1.7–2.4; P<0.0001) or MTGD (OR=2.9; 95% CI: 2.1–3.9; P<0.0001).

Conclusion: This study confirms that macrosomia is the main complication of DTGD. By contrast, DTGD was not associated with neonatal hypoglycemia and cesarean, while these complications were associated with MTGD.

Keywords: Complications; diet; gestational diabete

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About the article

Corresponding author: Pr. Olivier Sibony, Service de gynécologie-obstétrique, Hôpital Robert Debré, Assistance Publique-Hôpitaux de Paris, 48 Boulevard Sérurier, 75019 Paris, France, Tel.: +33 1 40 03 24 54, Fax: +33 1 40 03 53 76, E-mail:


Received: 2013-04-10

Accepted: 2013-10-09

Published Online: 2013-11-16

Published in Print: 2014-05-01


Citation Information: Journal of Perinatal Medicine, ISSN (Online) 1619-3997, ISSN (Print) 0300-5577, DOI: https://doi.org/10.1515/jpm-2013-0079. Export Citation

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