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Journal of Translational Internal Medicine

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Role of genetic factors in the development of acute respiratory distress syndrome

Chang Liu
  • Department of Intensive Care Unit, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Jian-guo Li
  • Corresponding author
  • Department of Intensive Care Unit, Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, China
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2015-04-24 | DOI: https://doi.org/10.4103/2224-4018.141831


Acute respiratory distress syndrome (ARDS) is not a genetic disease, but gene polymorphism influences the susceptibility, severity and prognosis of ARDS. It has been reported that the polymorphism of genes, such as angiotensin-converting enzyme and extracellular superoxide dismutase 3 genes, is related to ARDS. Research on the gene polymorphism of ARDS is currently in the preclinical stage, but it develops fast, In the future, ARDS-related gene polymorphism may play an important role in identifying susceptibility risk, assessing prognosis revealing new etiology and pathophysiological mechanisms, and optimizing diagnosis and treatment.

Keywords: Acute respiratory distress syndrome; genetics; gene polymorphism


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About the article

Published Online: 2015-04-24

Published in Print: 2014-09-01

Citation Information: Journal of Translational Internal Medicine, Volume 2, Issue 3, Pages 107–110, ISSN (Online) 2224-4018, DOI: https://doi.org/10.4103/2224-4018.141831.

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© 2015. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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