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Journal of Translational Internal Medicine

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Unusual presentation of nonalcoholic steatohepatitis-related cirrhosis in a patient with celiac disease and microscopic colitis

Muhammed Manzoor
  • Department of Hepatogastroentrology Sindh Institute of Urology and Transplantation, Karachi, Pakistan
/ Rajesh K. Wadhwa
  • Department of Hepatogastroentrology Sindh Institute of Urology and Transplantation, Karachi, Pakistan
/ Zaigham Abbas
  • Department of Hepatogastroentrology. Sindh Institute of Urology and Transplantation, Karachi, Pakistan
/ Syed Mujahid Hasan
  • Department of Hepatogastroentrolog, Sindh Institute of Urology and Transplantation, Karachi, Pakistan
/ Nasir Hasan Luck
  • Department of Hepatogastroentrology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan
/ Muhammed Mubarak
  • Corresponding author
  • Department of Histopathology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan
  • Email:
Published Online: 2015-04-24 | DOI: https://doi.org/10.4103/2224-4018.147747


Nonalcoholic steatohepatitis (NASH) is defined as the presence of hepatic steatosis and inflammation with hepatocyte injury (ballooning) with or without fibrosis. NASH is often a “silent” liver disease. Estimated prevalence of NASH ranges from 3% to 5% in different studies. The prevalence of NASH-related cirrhosis in the general population is not known. Herein, we report a case of a young female presented with NASH-related cirrhosis in the setting of poorly controlled celiac disease (CD) and microscopic colitis. A variety of liver abnormalities have been observed in patients with CD, but this unique constellation of the gut and liver pathologies has not been reported previously.

Keywords: Celiac disease; cirrhosis; fatty change; liver; microscopic colitis


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About the article

Published Online: 2015-04-24

Published in Print: 2014-12-01

Citation Information: Journal of Translational Internal Medicine, ISSN (Online) 2224-4018, DOI: https://doi.org/10.4103/2224-4018.147747. Export Citation

© 2015. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

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