Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Journal of Translational Internal Medicine

4 Issues per year

Open Access
Online
ISSN
2224-4018
See all formats and pricing
More options …

Gastritis profunda cystica presenting as gastric outlet obstruction and mimicking cancer: A case report

Muhammad Osama Butt
  • Corresponding author
  • Department of Hepatogastroenterology Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Nasir Hassan Luck
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Syed Mujahid Hassan
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Zaigham Abbas
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Muhammed Mubarak
  • Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2015-04-24 | DOI: https://doi.org/10.4103/2224-4018.154296

Abstract

Gastritis cystica profunda (GCP) is a rare, benign lesion of the stomach characterized by polypoid hyperplasia and/or ulcerated mucosal lesion and cystic dilatation of the gastric glands extending into the submucosa or muscularis propria of the stomach. Its etiology and pathogenesis are still incompletely understood. The most important factor is assumed to be a history of prior gastric surgery. We herein present a case of a young adult female with upper gastrointestinal (GI) symptoms. She underwent upper GI endoscopy twice, which revealed pyloric narrowing and intramural mass. Gastric endoscopic mucosal biopsies were performed, but no tumor was identified and her symptoms persisted. Imaging studies also revealed a mass lesion. Open laparotomy and partial gastrectomy with histopathology of the resected specimen revealed the true nature of the lesion. Surgery also improved her symptoms. GCP should be kept in the differential diagnosis of gastric mural mass lesions.

Keywords: Endoscopy; herniation; histopathology; partial gastrectomy; pyloric mass

References

  • 1. Littler ER, Gleibermann E. Gastritis cystica polyposa. (Gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrative epithelial hyperplasia). Cancer 1972;29:205-9.Google Scholar

  • 2. Franzin G, Novelli P. Gastritis cystica profunda. Histopathology 1981;5:535-47.Google Scholar

  • 3. Fonde EC, Rodning CB. Gastritis cystica profunda. Am J Gastroenterol 1986;81:459-64.Google Scholar

  • 4. Hirasaki S, Tanimizu M, Tsubouchi E, Nasu J, Masumoto T. Gastritis cystica polyposa concomitant with gastric inflammatory fibroid polyp occurring in an unoperated stomach. Intern Med 2005;44:46-9.Google Scholar

  • 5. Park CH, Park JM, Jung CK, Kim DB, Kang SH, Lee SW, et al. Early gastric cancer associated with gastritis cystica polyposa in the unoperated stomach treated by endoscopic submucosal dissection. Gastrointest Endosc 2009;69:e47-50.Google Scholar

  • 6. Tuncer K, Alkanat M, Musoglu A, Aydin A. Gastritis cystica polyposa found in an unoperated stomach: An unusual case treated by endoscopic polypectomy. Endoscopy 2003;35:882.Google Scholar

  • 7. Park JS, Myung SJ, Jung HY, Yang SK, Hong WS, Kim JH, et al. Endoscopic treatment of gastritis cystica polyposa found in an un-operated stomach. Gastrointest Endosc 2001;54:101-3.Google Scholar

  • 8. Ozenc AM, Ruacan S, Aran O. Gastritis cystica polyposa. Arch Surg 1988;123:372-3.Google Scholar

  • 9. Aoyagi K, Koufuji K, Yano S, Murakami N, Terasaki Y, Yamasaki Y, et al. Two cases of cancer in the remnant stomach derived from gastritis cystica polyposa. Kurume Med J 2000;47:243-8.Google Scholar

  • 10. Choi MG, Jeong JY, Kim KM, Bae JM, Noh JH, Sohn TS, et al. Clinical significance of gastritis cystica profunda and its association with Epstein-Barr virus in gastric cancer. Cancer 2012;118:5227-33.Web of ScienceGoogle Scholar

  • 11. Soares JB, Bastos P, Goncalves R. Menetrier disease with antrum polyposis and gastritis cystica profunda. Endoscopy 2012;44 (Suppl 2) UCTN:E56-7.Web of ScienceGoogle Scholar

  • 12. Lim JK, Jang YJ, Jung MK, Ryeom HK, Kim GC, Bae J. Menetrier disease manifested by polyposis in the gastric antrum and coexisting with gastritis cystica profunda. Gastrointest Endosc 2010;72:1098-100.Web of ScienceGoogle Scholar

  • 13. Yamashita M, Hirokawa M, Nakasono M, Kiyoku H, Sano N, Fujii M, et al. Gastric inverted hyperplastic polyp report of four cases and relation to gastritis cystica profunda. APMIS 2002;110:717-23.Google Scholar

  • 14. Ozturk A, Kaya C, Tahaoglu C. A rare stomach lesion: Gastritis cystica profunda. Int J Case Rep Med 2014. DOI: 10.5171/2014.249718. CrossrefGoogle Scholar

About the article

Published Online: 2015-04-24

Published in Print: 2015-03-01


Citation Information: Journal of Translational Internal Medicine, ISSN (Online) 2224-4018, DOI: https://doi.org/10.4103/2224-4018.154296.

Export Citation

© 2015. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

Citing Articles

Here you can find all Crossref-listed publications in which this article is cited. If you would like to receive automatic email messages as soon as this article is cited in other publications, simply activate the “Citation Alert” on the top of this page.

[1]
Tian-Jiao Guo
World Journal of Gastroenterology, 2015, Volume 21, Number 47, Page 13325

Comments (0)

Please log in or register to comment.
Log in