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Journal of Translational Internal Medicine

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Gastritis profunda cystica presenting as gastric outlet obstruction and mimicking cancer: A case report

Muhammad Osama Butt
  • Corresponding author
  • Department of Hepatogastroenterology Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
  • Email:
/ Nasir Hassan Luck
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
/ Syed Mujahid Hassan
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
/ Zaigham Abbas
  • Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
/ Muhammed Mubarak
  • Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi - 74200, Pakistan
Published Online: 2015-04-24 | DOI: https://doi.org/10.4103/2224-4018.154296


Gastritis cystica profunda (GCP) is a rare, benign lesion of the stomach characterized by polypoid hyperplasia and/or ulcerated mucosal lesion and cystic dilatation of the gastric glands extending into the submucosa or muscularis propria of the stomach. Its etiology and pathogenesis are still incompletely understood. The most important factor is assumed to be a history of prior gastric surgery. We herein present a case of a young adult female with upper gastrointestinal (GI) symptoms. She underwent upper GI endoscopy twice, which revealed pyloric narrowing and intramural mass. Gastric endoscopic mucosal biopsies were performed, but no tumor was identified and her symptoms persisted. Imaging studies also revealed a mass lesion. Open laparotomy and partial gastrectomy with histopathology of the resected specimen revealed the true nature of the lesion. Surgery also improved her symptoms. GCP should be kept in the differential diagnosis of gastric mural mass lesions.

Keywords: Endoscopy; herniation; histopathology; partial gastrectomy; pyloric mass


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About the article

Published Online: 2015-04-24

Published in Print: 2015-03-01

Citation Information: Journal of Translational Internal Medicine, ISSN (Online) 2224-4018, DOI: https://doi.org/10.4103/2224-4018.154296. Export Citation

© 2015. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

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