Jump to ContentJump to Main Navigation
Show Summary Details


Offizielles Organ der Deutschen Vereinten Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL) und affiliiert mit der Österreichischen Gesellschaft für Laboratoriumsmedizin und Klinische Chemie (ÖGLMKC)

Editor-in-Chief: Schuff-Werner, Peter

Editorial Board Member: Ahmad-Nejad, Parviz / Bidlingmaier, Martin / Karsten, Conrad / Fraunberger, Peter / Ghebremedhin, Beniam / Kiehntopf, Michael / Klein, Hanns-Georg / Klouche, Mariam / Kohse, Klaus P. / Kratzsch, Jürgen / Luppa, Peter B. / März, Winfried / Nebe, Carl Thomas / Orth, Matthias / Ruf, Andreas / Steimer, Werner / Stieber, Petra / Weber, Bernard / Wieland, Eberhard / Sack, Ulrich / Tumani, Hayrettin / Zettl, Uwe K.

IMPACT FACTOR 2015: 0.104
5-year IMPACT FACTOR: 0.180

SCImago Journal Rank (SJR) 2014: 0.151
Source Normalized Impact per Paper (SNIP) 2014: 0.172
Impact per Publication (IPP) 2014: 0.313

99,00 € / $149.00 / £75.00*

See all formats and pricing


Select Volume and Issue


30,00 € / $42.00 / £23.00

Get Access to Full Text

Immunosuppressant drug monitoring – a routine undertaking?1

Christoph Seger1 / Michael Vogeser12

1Institute of Medical and Chemical Laboratory Diagnostics (ZIMCL), University Hospital Innsbruck, Innsbruck, Austria

2Institute of Clinical Chemistry, Hospital of the University of Munich, Munich, Germany

Correspondence: Christoph Seger, PhD, Institute of Medical and Chemical Laboratory Diagnostics (ZIMCL), University Hospital Innsbruck, Innsbruck, Austria Tel.: +43 51250481155 Fax: +43 51250424088

Citation Information: LaboratoriumsMedizin. Volume 34, Issue 3, Pages -–-, ISSN (Online) 1439-0477, ISSN (Print) 0342-3026, DOI: 10.1515/jlm.2010.027et, July 2010

Publication History

Published Online:


The quantitative assessment of immunosuppressant drug levels is still one of the most challenging therapeutic drug monitoring procedures in clinical routine. During the past years, several technical developments matured to usable methods. In addition to immunoassays, liquid chromatography-tandem mass spectrometry has become a key method in immunosuppressant therapeutic drug monitoring. This overview should aid in understanding the advantages and disadvantages of the various assays and methods. UK-NEQAS proficiency testing results are used for an inter-assay comparison approach.

Keywords: immunoassays; immunosuppressant drugs; liquid chromatography-tandem mass spectrometry (LC-MS/MS); proficiency testing; tandem mass spectrometry; therapeutic drug monitoring

Comments (0)

Please log in or register to comment.