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LaboratoriumsMedizin - Journal of Laboratory Medicine

Offizielles Organ der Deutschen Vereinten Gesellschaft für Klinische Chemie und Laboratoriumsmedizin e.V. (DGKL) und affiliiert mit der Österreichischen Gesellschaft für Laboratoriumsmedizin und Klinische Chemie (ÖGLMKC)

Editor-in-Chief: Schuff-Werner, Peter

Editorial Board Member: Ahmad-Nejad, Parviz / Bidlingmaier, Martin / Borucki, Katrin / Karsten, Conrad / Fraunberger, Peter / Ghebremedhin, Beniam / Holdenrieder, Stefan / Kiehntopf, Michael / Klein, Hanns-Georg / Klouche, Mariam / Kohse, Klaus P. / Kratzsch, Jürgen / Luppa, Peter B. / März, Winfried / Nebe, Carl Thomas / Orth, Matthias / Ruf, Andreas / Sack, Ulrich / Steimer, Werner / Weber, Bernard / Wieland, Eberhard / Tumani, Hayrettin / Zettl, Uwe K.

6 Issues per year


IMPACT FACTOR 2016: 0.176
5-year IMPACT FACTOR: 0.200

CiteScore 2016: 0.27

SCImago Journal Rank (SJR) 2015: 0.133
Source Normalized Impact per Paper (SNIP) 2015: 0.281

Online
ISSN
1439-0477
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In This Section
Volume 35, Issue 1 (Jan 2011)

Issues

Challenges in the measurement of serum testosterone concentrations as a biomarker of men's health1

Robin Haring
  • Corresponding author
  • Institute for Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany
  • Email:
/ Christin Spielhagen
  • Institute for Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany
/ Matthias Nauck
  • Institute for Clinical Chemistry and Laboratory Medicine, University of Greifswald, Greifswald, Germany
Published Online: 2011-04-05 | DOI: https://doi.org/10.1515/JLM.2011.001_engl

Abstract

Male testosterone concentrations gained recent attention in the field of andrology. Various epidemiological cohort studies presented associations of low serum testosterone concentrations with incident cardiovascular risk factors and increased mortality risk. Furthermore, low serum testosterone concentrations are integral part for the diagnosis of late-onset hypogonadism. Because of their high validity and throughput, mass spectrometry assays have replaced conventional immunoassays for testosterone measurement, and are believed to become the "gold standard" for sex hormone quantitation. This article will focus on challenges in the measurement of serum testosterone concentrations and will provide practical information on the interpretation of serum testosterone measurements.

Keywords:: androgens; biomarker; immunoassay; mass spectrometry; testosterone

About the article

Korrespondenz: Dr. rer. med. Robin Haring, Institut für Klinische Chemie und Laboratoriumsmedizin, Ernst-Moritz-Arndt-Universität Greifswald, Ferdinand-Sauerbruch-Straße, 17475 Greifswald. Telefon: +49-3834-8619656, Fax: +49-3834-865502


Published Online: 2011-04-05

Published in Print: 2011-02-01



Citation Information: LaboratoriumsMedizin, ISSN (Online) 1439-0477, ISSN (Print) 0342-3026, DOI: https://doi.org/10.1515/JLM.2011.001_engl. Export Citation

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