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BY-NC-ND 3.0 license Open Access Published by De Gruyter June 7, 2011

Thrombocytopathy: an update1

  • Tim Drogies EMAIL logo , Leanthe Braunert , Joachim Thiery and Mathias Brügel
From the journal LaboratoriumsMedizin

Abstract

“Thrombocytopathia” describes inherited or acquired functional disorders of platelets. The complexity of functional and metabolic processes in platelets is associated with a multitude of possible pathologic disturbances, showing a high variability in the clinical picture. The diagnosis of thrombocytopathies by existing laboratory methods is limited by variable sensitivities and specificities for various pathophysiologic backgrounds. Furthermore, the clinical evaluation of laboratory results is complex because of high intra- and interindividual variability of the platelet function. In daily routine diagnostics, a detailed patient history and clinical examination combined with aggregometry-based laboratory methods remains the central approach to diagnose a platelet function disorder.


Korrespondenz: Dr. Tim Drogies, Institut für Laboratoriumsmedizin, Klinische Chemie und Molekulare Diagnostik, Universitätsklinikum Leipzig, AöR, Paul-List-Str. 13–15, 04103 Leipzig, Tel.: +49-341-9722463, Fax: +49-341-9722209

Published Online: 2011-06-07
Published in Print: 2011-April

© 2011 Walter de Gruyter GmbH & Co. KG, Berlin/New York

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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