Abstract
“Thrombocytopathia” describes inherited or acquired functional disorders of platelets. The complexity of functional and metabolic processes in platelets is associated with a multitude of possible pathologic disturbances, showing a high variability in the clinical picture. The diagnosis of thrombocytopathies by existing laboratory methods is limited by variable sensitivities and specificities for various pathophysiologic backgrounds. Furthermore, the clinical evaluation of laboratory results is complex because of high intra- and interindividual variability of the platelet function. In daily routine diagnostics, a detailed patient history and clinical examination combined with aggregometry-based laboratory methods remains the central approach to diagnose a platelet function disorder.
© 2011 Walter de Gruyter GmbH & Co. KG, Berlin/New York
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