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Linguistics Vanguard

A Multimodal Journal for the Language Sciences

Editor-in-Chief: Bergs, Alexander / Cohn, Abigail C. / Good, Jeff


CiteScore 2018: 0.95

SCImago Journal Rank (SJR) 2018: 0.381
Source Normalized Impact per Paper (SNIP) 2018: 0.841

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2199-174X
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Perplexity – a new predictor of cognitive changes in spoken language? – results of the Interdisciplinary Longitudinal Study on Adult Development and Aging (ILSE)

Claudia Frankenberg / Jochen Weiner / Tanja Schultz / Maren Knebel
  • Heidelberg University, Section of Geriatric Psychiatry, Heidelberg, Germany
  • Goethe Univerisity Frankfurt, Frankfurt Forum for Interdisciplinary Ageing Research, Frankfurt, Germany
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Christina Degen / Hans-W. Wahl / Johannes Schroeder
Published Online: 2019-06-22 | DOI: https://doi.org/10.1515/lingvan-2018-0026

Abstract

In addition to memory loss, progressive deterioration of speech and language skills is among the main symptoms at the onset of Alzheimer’s disease (AD) as well as in mild cognitive impairment (MCI). Detailed interview analyses demonstrated early symptoms years before the onset of AD/MCI. Automatic speech processing could be a promising approach to identifying underlying mechanisms in larger studies or even support diagnostics. Perplexity as a measure of predictability of text could be a sensitive indicator of cognitive deterioration. Therefore, voice recordings from the Interdisciplinary Longitudinal Study on Adult Development and Aging were analyzed with regard to neuropsychological parameters in participants that develop MCI/AD or remain cognitively healthy. Preliminary results indicate that perplexity predicts severity of cognitive deficits and information processing speed obtained 10–12 years later in participants who developed MCI/AD in contrast to those who stayed healthy. Findings support the heuristic value of research on the diagnostic potential of automatic speech processing.

Keywords: language and aging; speech processing; Alzheimer’s disease; mild cognitive impairment

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About the article

Received: 2018-05-15

Accepted: 2019-01-07

Published Online: 2019-06-22


Citation Information: Linguistics Vanguard, Volume 5, Issue s2, 20180026, ISSN (Online) 2199-174X, DOI: https://doi.org/10.1515/lingvan-2018-0026.

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