Jump to ContentJump to Main Navigation
Show Summary Details

Macedonian Veterinary Review

The Journal of the Faculty of Veterinary Medicine-Skopje at the Ss. Cyril and Methodius University in Skopje

2 Issues per year


SCImago Journal Rank (SJR) 2015: 0.203
Source Normalized Impact per Paper (SNIP) 2015: 0.565
Impact per Publication (IPP) 2015: 0.325

Open Access
Online
ISSN
1857-7415
See all formats and pricing

A Report of a Hepatozoon Canis Infection in a Dog with Transmissible Venereal Tumour

Namakkal Rajamanickam Senthil
  • Corresponding author
  • Centralised Clinical Laboratory Madras Veterinary College, Chennai - 600007, Tamil Nadu, India
  • Email:
/ Subramanian Subapriya
  • Centralised Clinical Laboratory Madras Veterinary College, Chennai - 600007, Tamil Nadu, India
/ Subbaiah Vairamuthu
  • Centralised Clinical Laboratory Madras Veterinary College, Chennai - 600007, Tamil Nadu, India
Published Online: 2015-11-18 | DOI: https://doi.org/10.14432/j.macvetrev.2015.06.046

Abstract In the present study, a case of a Hepatozoan canis infection in a dog with a sexually transmissible venereal tumour is reported. Haematological examination revealed marked decrease in haemoglobin, PCV and RBC counts and the blood smear revealed rouleaux formation of RBC, hypochromasia, leptocytes and neutrophilia. Neutrophils were parasitized with both non-nucleated and stained nucleated forms of H. canis. Serum biochemistry results showed elevated levels of alkaline phosphatise, whereas blood urea nitrogen, creatinine, total protein, albumin and globulin were in the normal range.

Keywords: canine; transmissible venereal tumour; Hepatozoon canis

References

  • 1. Goldschmidt, M. H., Hendrick, M. J. (2002). Tumours of the skin and soft tissues. In: Meuton, D. J. (Ed.), 4th ed., Tumours in Domestic Animals. (pp. 45-118). Press, Iowa. Iowa State.

  • 2. Chu, R.M., Sun, T.J., Yang, H.Y., Wang, D.G., Liao, K.W., Chuang, T.F., Lin, C.H., Lee, W.C. (2001). Heat shock proteins in canine transmissible venereal tumor. Vet. Immunol Immunopathol. 82, 9-21. http://dx.doi.org/10.1016/S0165-2427(01)00327-0 [Crossref]

  • 3. Cohen D. (1985). The canine transmissible venereal tumor: A unique result of tumour progression. Adv Cancer Res. 43, 75-112. http://dx.doi.org/10.1016/s0065-230x(08)60943-4 [Crossref]

  • 4. Gavazza, A., Bizzeti, M., Papini, R. (2003). Observations on dogs found naturally infected with Hepatozoon canis in Italy. Rev. Méd. Vét. 154, 565-571.

  • 5. Baneth, G., Samish,M., Shkap, V., (2007). Life cycle of Hepatozoon canis (apicomplexa: adeleorina: hepatozoidae) in the tick Rhipicephalus sanguineus and domestic dog (Canis familiaris). J. Parasitol. 93 (2): 283-299. http://dx.doi.org/10.1645/GE-494R.1 PMid:17539411 [Crossref] [Web of Science]

  • 6. Stettner, N., Brenner, O., Eilam, R., Harmelin, A. (2005). Pegylated liposomal doxorubicin as a chemotherapeutic agent for treatment of canine transmissible venereal tumor in murine models. J. Vet. Med. 67, 1133-1139. http://dx.doi.org/10.1292/jvms.67.1133 [Crossref]

  • 7. Stockmann, D., Ferrari, H.F., Andrade, A.L., Lopes, R.A., Cardoso, T.C., Luvizotto, M.C.R. (2011). Canine transmissible venereal tumors: Aspects related to programmed cell death. Braz J. Vet. Pathol. 4, 67-75.

  • 8. Oruc, E., Saglam, Y.S., Cengiz, M., Polat, B. (2011). Cytological diagnosis of breast metastasis of transmissible venereal tumor by fine needle aspiration and the treatment with vincristine sulphate in a dog. Ankara Üniv Vet Fak Derg. 6, 63-69.

  • 9. Kerr, M.G. (2002). Clinical biochemistry and haematology. In: (2nd Ed.), Veterinary Laboratory Medicine (pp.135-147). Blackwell Science Ltd, USA.

  • 10. Sarma, K., Mondal, D.B., Saravanan, M., Kumar, M., Mahendran, K. ( 2012). Haemato-biochemical changes in Hepatozoon canis infected dog before and after therapeutic management J. Vet. Parasitol. 26 (1): 35-38.

  • 11. Kose, A.M, Cizmeci, S.U, Aydin, I, Dinc, D.A, Maden, M., Kanat, O. (2013). Disseminated metastatic transmissible venereal tumour in a bitch Eurasian J .Vet. Sci. 29, 1, 053-057.

  • 12. Paramjit K., Deshmukh, S., Rajsukhbir, S., Bansal, B.K., Randhawa, C.S., Singla, L.D. (2012). Para-clinico-pathological observations of insidious incidence of canine hepatozoonosis from a mongrel dog: a case report. J .Parasit. Dis. 36(1): 135-138. http://dx.doi.org/10.1007/s12639-011-0092-x PMid:23543040 PMCid:PMC3284626 [Crossref]

  • 13. Ruiz, M.F., Zimmermann, R.N., Aguirre, F.O., Forti, M.S. (2013). Hepatozoon canis asociado a un tumor venéreo transmisible: singular hallazgo. Vet. Arg. 30, 306.

  • 14. Baneth, G., Weigler, B. (1997). Retrospective casecontrol study of hepatozoonosis in dogs in Israel. J. Vet. Intern. Med. 11, 365-370. http://dx.doi.org/10.1111/j.1939-1676.1997.tb00482.x PMid:9470163 [Crossref]

  • 15. Gondim, L. F. P., Kohayagawa, A., Alencar, N. X., Biondo, A. W., Takahira, R. F., Franco, S. R. V. (1998). Canine hepatozoonosis in Brazil: description of eight naturally occurring cases. Vet. Parasitol. 74, 319-323. http://dx.doi.org/10.1016/S0304-4017(96)01120-X [Crossref]

  • 16. Marino, G., Gaglio, G., Zanghi, A. (2012). Clinicopathological study of canine transmissible venereal tumour in leishmaniotic dogs. J. Small Anim. Pract. 53, 323-327. http://dx.doi.org/10.1111/j.1748-5827.2012.01201.x PMid:22489831 [Crossref] [Web of Science]

  • 17. Raghunath, M., Sudha Rani Chowdhary, Ch., Vidya Sagar, P., Ravi Kumar, P. (2015). Genital and extra genital TVT in a bitch- a case report. Sch J Agric Vet Sci. 2(1B): 61-62.

About the article

Received: 2015-03-17

Revised: 2015-06-03

Accepted: 2015-06-10

Published Online: 2015-11-18

Published in Print: 2015-10-01


Citation Information: Macedonian Veterinary Review, ISSN (Online) 1857-7415, DOI: https://doi.org/10.14432/j.macvetrev.2015.06.046. Export Citation

© 2015. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License. (CC BY-NC-ND 4.0)

Comments (0)

Please log in or register to comment.
Log in