Jump to ContentJump to Main Navigation
Show Summary Details
More options …

Open Medicine

formerly Central European Journal of Medicine

Editor-in-Chief: Darzynkiewicz, Zbigniew

1 Issue per year


IMPACT FACTOR 2016 (Open Medicine): 0.294
IMPACT FACTOR 2016 (Central European Journal of Medicine): 0.116

CiteScore 2016: 0.28

SCImago Journal Rank (SJR) 2015: 0.140
Source Normalized Impact per Paper (SNIP) 2015: 0.154

Open Access
Online
ISSN
2391-5463
See all formats and pricing
More options …
Volume 3, Issue 4

Issues

Intracranial meningioma in a patient with osteogenesis imperfecta

Parmenion Tsitsopoulos
  • Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ioannis Anagnostopoulos
  • Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Vasileios Tsitouras
  • Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
/ Ioannis Venizelos / Philippos Tsitsopoulos
  • Department of Neurosurgery, Hippokratio General Hospital, Aristotle University Medical School, 54642, Thessaloniki, Greece
  • Email
  • Other articles by this author:
  • De Gruyter OnlineGoogle Scholar
Published Online: 2008-10-22 | DOI: https://doi.org/10.2478/s11536-008-0053-7

Abstract

Osteogenesis imperfecta (OI) is a heritable disorder characterized mainly by connective tissue manifestations. In dinstinct cases, several neurological features have also been described. A 46-year-old male with a known family history of OI type I presented with progressive gait disturbances and diminished muscle strength. Brain MRI scans revealed an infiltrative intracranial mass occupying both frontoparietal lobes. The patient underwent surgical intervention. The histological diagnosis was an atypical (Grade II) meningioma. The bony parts demonstrated a mixture of osseous defects due to OI and infiltration by the tumor. At one-year follow up the patient′s muscle power partially returned while repeat MRI scans were negative for tumor recurrence.

Keywords: Osteogenesis Imperfecta; Meningioma; Tumor; Bone anomalies; Connective tissue

  • [1] Rausch F., Glorieux F.H., Osteogenesis imperfecta, Lancet, 2004, 363, 1377–1385 http://dx.doi.org/10.1016/S0140-6736(04)16051-0CrossrefGoogle Scholar

  • [2] Charmas L.R., Marini J.C., Communicating hydrocephalus, basilar invagination, and other neurologic features in osteogenesis imperfecta, Neurology, 1993, 43, 2603–2608 Google Scholar

  • [3] Sillence D., Osteogenesis imperfecta: An expanding panorama of variants, Clin. Orthop., 1981, 159, 11–25 Google Scholar

  • [4] Kovero O., Pynnönen S., Kuurila-Svahn K., Kaitila I., Valtimo-Sirén J., Skull base abnormalities in osteogenesis imperfecta: a cephalometric evaluation of 54 patients and 108 control volunteers, J. Neurosurg,. 2006, 105, 361–370 http://dx.doi.org/10.3171/jns.2006.105.3.361CrossrefGoogle Scholar

  • [5] Charmas L.R., Marini JC., Neurologic profile in osteogenesis imperfecta, Connect. Tissue Res., 1995, 31(4), S23–26 http://dx.doi.org/10.3109/03008209509116828CrossrefGoogle Scholar

  • [6] De Campos J-M., Lopez Ferro M.O., Burzaco J.A., Boixados J.R., Spontaneous carotid-cavernous fistula in osteogenesis imperfecta, J. Neurosurg., 1982, 56, 590–593 http://dx.doi.org/10.3171/jns.1982.56.4.0590CrossrefGoogle Scholar

  • [7] Korkko J., Ala-Kokko L., De Paepe A., Nuytinck L., Earley J., Prockop D.J., Analysis of the COLIA1 and COLIA2 genes by PCR amplification and scanning by conformation-sensitive gel electrophoresis identifies only COLIA1 mutation in 15 patients with osteogenesis imperfecta type I: identification of common sequences of null allele-mutations, Am. J. Hum. Genet., 1998, 62, 98–110 http://dx.doi.org/10.1086/301689Google Scholar

  • [8] Byers P.H., Osteogenesis imperfecta: perspectives and opportunities, Curr. Opin. Pediatr., 2000, 12, 603–609 http://dx.doi.org/10.1097/00008480-200012000-00016CrossrefGoogle Scholar

  • [9] Mc Allion S.J., Paterson C.R., Causes of death in osteogenesis imperfecta, J. Clin. Pathol., 1996, 49, 627–630 http://dx.doi.org/10.1136/jcp.49.8.627CrossrefGoogle Scholar

  • [10] Burgeson R.E., Nimni M.E., Collagen types. Molecular structure and tissue distribution, Clin. Orthop., 1992, 282, 250–272 Google Scholar

  • [11] Turnbull D.K., Shepherd D.B., Post-dural puncture headache: pathogenesis, prevention and treatment, Br. J. Anaesthesia, 2003, 91(5),718–729 http://dx.doi.org/10.1093/bja/aeg231CrossrefGoogle Scholar

  • [12] Frank E., Berger T., Tew J.M., Basilar impression and platybasia in osteogenesis imperfecta tarda, Surg. Neurol., 1981, 17, 116–119 http://dx.doi.org/10.1016/S0090-3019(82)80033-5CrossrefGoogle Scholar

  • [13] Pozo J., Crockard H., Ransford A.O., Basilar impression in ostegenesis imperfecta: a report of three cases in one family, J. Bone Joint Surg. [Br], 1984, 66, 233–238 Google Scholar

  • [14] Simon M., Boström J.P., Hartman C., Molecular genetics of meningiomas: From basic research to potential clinical application, Neurosurgery, 2007, 60, 787–798 http://dx.doi.org/10.1227/01.NEU.0000255421.78431.AEWeb of ScienceCrossrefGoogle Scholar

  • [15] Reeder J., Orwoll E., Adults with osteogenesis imperfecta, NEJM, 2006, 355, 26 http://dx.doi.org/10.1056/NEJMicm062996CrossrefGoogle Scholar

About the article

Published Online: 2008-10-22

Published in Print: 2008-12-01


Citation Information: Open Medicine, Volume 3, Issue 4, Pages 517–520, ISSN (Online) 2391-5463, DOI: https://doi.org/10.2478/s11536-008-0053-7.

Export Citation

© 2008 Versita Warsaw. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

Comments (0)

Please log in or register to comment.
Log in