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Open Medicine

formerly Central European Journal of Medicine

Editor-in-Chief: Darzynkiewicz, Zbigniew


IMPACT FACTOR 2018: 1.221

CiteScore 2018: 1.01

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ICV 2017: 152.94

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2391-5463
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Volume 7, Issue 2

Issues

Volume 10 (2015)

Neutrophil to lymphocyte count ratio as a biomarker of bacterial infections

Michal Holub
  • Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague and University Hospital Bulovka, CZ-180 81, Prague, Czech Republic
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/ Ondřej Beran
  • Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague and University Hospital Bulovka, CZ-180 81, Prague, Czech Republic
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/ Nikola Kaspříková
  • Institute of Biophysics and Informatics, First Faculty of Medicine, Charles University in Prague, CZ-120 00, Prague, Czech Republic
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/ Pavel Chalupa
  • Department of Infectious and Tropical Diseases, First Faculty of Medicine, Charles University in Prague and University Hospital Bulovka, CZ-180 81, Prague, Czech Republic
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Published Online: 2012-02-03 | DOI: https://doi.org/10.2478/s11536-012-0002-3

Abstract

The implementation of new markers of bacterial infection into clinical practice is hindered by their costs. We assessed the potential use of the neutrophil to lymphocyte count ratio (NLCR) to discriminate between bacterial and viral infections. NLCR was evaluated in 45 patients with bacterial infections: 24 patients with viral infections and 18 healthy adults. The medians of NLCR were 11.73 in bacterial infections, 2.86 in viral infections and 1.86 in controls. The NLCR cut-off value of 6.2 exhibited a sensitivity value of 0.91 and a specificity value of 0.96 for bacterial infection. These results suggest a diagnostic potential for NLCR.

Keywords: Bacterial infection; Viral infection; Laboratory diagnosis; Marker; Neutrophil to lymphocyte ratio

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About the article

Published Online: 2012-02-03

Published in Print: 2012-04-01


Citation Information: Open Medicine, Volume 7, Issue 2, Pages 258–261, ISSN (Online) 2391-5463, DOI: https://doi.org/10.2478/s11536-012-0002-3.

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© 2012 Versita Warsaw. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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