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Open Medicine

formerly Central European Journal of Medicine

Editor-in-Chief: Darzynkiewicz, Zbigniew

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Density of nerve fibres in eutopic endometrium in women with endometriosis

1Faculty of Medicine, Clinic of Obstetrics and Gynecology, Vilnius University, Antakalnio 57, Vilnius, Lithuania, LT-10207

© 2013 Versita Warsaw. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. (CC BY-NC-ND 3.0)

Citation Information: Open Medicine. Volume 8, Issue 2, Pages 141–145, ISSN (Online) 2391-5463, DOI: 10.2478/s11536-012-0122-9, January 2013

Publication History

Published Online:


Endometriosis is the disease which usually takes a wide range of time to be diagnosed. Recently, the investigators found that endometriosis could be diagnosed using the density of nerve fibers in eutopic endometrium after taking endometrium bioptate. The aim of the article is to summarize the existing literature on density of nerve fibers in eutopic endometrium in women with and without endometriosis. In this review were involved only those studies which used the same exclusion criteria and the same technology to detect nerve fibers in eutopic endometrium. Our review confirmed the position of all studies’ results that detection of specific nerve fibers within eutopic endometrium using minimally invasive endometrial biopsy technique could be widely used in clinical practice to diagnose endometriosis with high specificity and sensitivity.

Keywords: Endometriosis; Density of nerve fibers; Endometrial biopsy

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