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MitoProteomics: New Insights in Infection Biology

Santi M. Mandal / Amit K. Mandal / Keshab C. Mondal / Bikas R. Pati
Published Online: 2014-11-12 | DOI: https://doi.org/10.2478/orpr-2014-0002


Mitochondria are the organelles as central hubs of energy production, apoptosis regulation, and Ca++ signaling, therefore prime targets of pathogens to destroy the signaling network as earliest for their survivability. Recently, several proteomics approaches have been undertaken for rapid identification and analyses of disease manifestation in infection biology. Here, we have summarized the mostly popular topdown proteomics approaches including methodology to available database for mitochondrial signaling network analyses during host-pathogen interaction and a key tool for rapid biomarker identification.

Keywords : Infection biology; MitoProteomics; tandem mass spectrometry; top-down proteomics


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About the article

Received: 2014-06-08

Accepted: 2014-08-08

Published Online: 2014-11-12

Citation Information: Organelles Proteomics, Volume 1, Issue 1, ISSN (Online) 2084-722X, DOI: https://doi.org/10.2478/orpr-2014-0002.

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© 2014 Santi M. Mandal et al.. This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. BY-NC-ND 3.0

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