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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Stohner, Jürgen

12 Issues per year


IMPACT FACTOR 2016: 2.626
5-year IMPACT FACTOR: 3.210

CiteScore 2017: 3.42

SCImago Journal Rank (SJR) 2017: 1.212
Source Normalized Impact per Paper (SNIP) 2017: 1.546

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1365-3075
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Volume 73, Issue 2

Issues

Some newer aspects of organozirconium chemistry of relevance to organic synthesis. Zr-Catalyzed enantioselective carbometallation

Ei-ichi Negishi
  • Corresponding author
  • Herbert C. Brown Laboratories of Chemistry, Purdue University, West Lafayette, Indiana 47907-1393, USA
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Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200173020239

The reaction of terminal alkenes with trialkylalanes in the presence of chiral (NMI) 2ZrCl2 has been shown to be 70-75% ee for methylalumination and 90-95% ee for ethyl- and higher alkylalumination. It must involve an acyclic bimetallic process. Its scope, limitations, and applications to some natural products syntheses are discussed.

Conference

International Conference on Organometallic Chemistry (XIX ICOMC), International Conference on Organometallic Chemistry, ICOMC, Organometallic Chemistry, XIXth, Shanghai, China, 2000-07-23–2000-07-28

About the article

Published Online: 2009-01-01

Published in Print: 2001-01-01


Citation Information: Pure and Applied Chemistry, Volume 73, Issue 2, Pages 239–242, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200173020239.

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