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Pure and Applied Chemistry

The Scientific Journal of IUPAC

Ed. by Burrows, Hugh / Stohner, Jürgen

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Volume 74, Issue 10


Natural and synthetic substances related to human health (IUPAC Technical Report)

J. G. Topliss / A. M. Clark / E. Ernst / C. D. Hufford / G. A. R. Johnston / J. M. Rimoldi / B. J. Weimann
Published Online: 2009-01-01 | DOI: https://doi.org/10.1351/pac200274101957

There is a widespread belief on the part of the general public that natural substances are inherently superior to synthetic substances with regard to efficacy and safety in matters related to human health. This question is examined by reviewing the therapeutic use of drugs and herbal medicine preparations, the role of vitamins and nutrients, and the effects of toxic substances. A comparison of the characteristics of natural and synthetic substances within these categories shows a similar range of favorable and unfavorable effects. It is apparent that molecular structure and dose determine the effect of substances on human health, not whether they are of natural or synthetic origin.

Project Year: 1998, Project Code: 700/2/98

About the article

Published Online: 2009-01-01

Published in Print: 2002-01-01

Citation Information: Pure and Applied Chemistry, Volume 74, Issue 10, Pages 1957–1985, ISSN (Online) 1365-3075, ISSN (Print) 0033-4545, DOI: https://doi.org/10.1351/pac200274101957.

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